Results 51 to 60 of about 779 (157)

A systematic approach to cancer: evolution beyond selection

Clinical and Translational Medicine, Volume 6, Issue 1, December 2017., 2017
AbstractCancer is typically scrutinized as a pathological process characterized by chromosomal aberrations and clonal expansion subject to stochastic Darwinian selection within adaptive cellular ecosystems. Cognition based evolution is suggested as an alternative approach to cancer development and progression in which neoplastic cells of differing ...
William B. Miller Jr., John S. Torday
wiley   +1 more source

Sputnik 3 virophage isolation.

, 2013
(A) Schematic summarizing the protocol used in this study for the isolation of virophage. Observations of the virophage isolated in this study by (B) transmission electron microscopy of negatively stained particles (A, scale bar 200 nm) and (C ...
Morgan Gaia (402516), Ghislain Fournous (223031), Isabelle Pagnier (402517), Angélique Campocasso (402518), Bernard La Scola (3832), Didier Raoult (3833)   +5 more
core   +1 more source

A virophage cross-species infection through mutant selection represses giant virus propagation, promoting host cell survival

, 2020
International audienceVirus adaptation to new hosts is a major cause of infectious disease emergence. This mechanism has been intensively studied in the context of zoonotic virus spillover, due to its impact on global health.
Colson, Philippe, Mougari, Said, Chelkha, Nisrine, Abrahao, Jonatas, La Scola, Bernard, Sahmi-Bounsiar, Dehia, Di Pinto, Fabrizio   +6 more
core   +1 more source

Virophage replication mode determines ecological and evolutionary changes in a host-virus-virophage system

bioRxiv
Giant viruses can control their eukaryotic host populations, shaping the ecology and evolution of aquatic microbial communities. Understanding the impact of the viruses’ own parasites, the virophages, on their control of microbial communities remains a ...
A. del Arco, Lutz Becks
semanticscholar   +1 more source

The Common Ancestor of Archaea and Eukarya Was Not an Archaeon

Archaea, Volume 2013, Issue 1, 2013., 2013
It is often assumed that eukarya originated from archaea. This view has been recently supported by phylogenetic analyses in which eukarya are nested within archaea. Here, I argue that these analyses are not reliable, and I critically discuss archaeal ancestor scenarios, as well as fusion scenarios for the origin of eukaryotes.
Patrick Forterre, Gustavo Caetano-Anollés   +1 more
wiley   +1 more source

Smaller Fleas: Viruses of Microorganisms

Scientifica, Volume 2012, Issue 1, 2012., 2012
Life forms can be roughly differentiated into those that are microscopic versus those that are not as well as those that are multicellular and those that, instead, are unicellular. Cellular organisms seem generally able to host viruses, and this propensity carries over to those that are both microscopic and less than truly multicellular.
Paul Hyman, Stephen T. Abedon, Hirofumi Akari, Joaquim Ruiz Blazquez, Giuseppe Comi, Ariel M. Silber   +5 more
wiley   +1 more source

Amoebae, Giant Viruses, and Virophages Make Up a Complex, Multilayered Threesome

Frontiers in Cellular and Infection Microbiology, 2018
Viral infection had not been observed for amoebae, until the Acanthamoeba polyphaga mimivirus (APMV) was discovered in 2003. APMV belongs to the nucleocytoplasmatic large DNA virus (NCLDV) family and infects not only A.
Jan Diesend, Janis Kruse, Monica Hagedorn, Christian Hammann   +3 more
doaj   +1 more source

Variations of the Virome in Raw and Treated Water: A One‐Year Follow‐Up at Six Different Drinking Water Treatment Plants

Environmental Microbiology Reports, Volume 17, Issue 6, December 2025.
This paper describes monitoring of outgoing water from drinking water treatment plants, geographically spread over half of Sweden and sampled every other month for 1 year. We found differences in the virome from the different water sources from each plant as well as differences in virus size and seasonal variation, where we also could detect viruses in
Fredy Saguti, Hao Wang, Marianela Patzi Churqui, Timur Tunovic, Linda Holmer, Ämma Pettersson, Caroline Schleich, Britt‐Marie Pott, Olof Bergstedt, Kristina Nyström, Heléne Norder   +10 more
wiley   +1 more source

Viral metagenomics of Okavango Delta water pans reveal novel insights into wildlife disease potential

iMetaOmics, Volume 2, Issue 2, June 2025.
Botswana's Seronga region saw a mass elephant die‐off potentially linked to water sources. This study analyzes Okavango Delta metagenomes, uncovering a diversity of viruses and harmful pathogens. Findings highlight the importance of understanding viral ecology in these waters and support One Health's objective in protecting human, animal, and ecosystem
Emilie J. Skoog, Kenosi Kebabonye, Benjamin Klempay, Mangaliso Gondwe, Kaelo Makati, Nlingisisi Babayani, Mosimanegape Jongman, Jeff Bowman, Lihini Aluwihare   +8 more
wiley   +1 more source

Rio Negro virophage: Sequencing of the near complete genome and transmission electron microscopy of viral factories and particles

Brazilian Journal of Microbiology, 2018
Rio Negro virophage (RNV) was co-isolated with a strain of mimivirus named sambavirus, from Brazilian Amazon. We report the near complete genome sequence of RNV, the first virophage isolated in Brazil. We also present new microscopical data demonstrating
I. Borges, F. Assis, Ludmila Karen dos Santos Silva, J. Abrahão   +3 more
semanticscholar   +1 more source