Results 221 to 230 of about 1,093,531 (288)

32 minutes of participants interactions at #i2k2020 virtual conference

, 2020
Jerome Mutterer
openalex   +2 more sources

TargetGen‐RNN model discovers novel antibiotic compound targeting drug‐resistant Staphylococcus aureus

Interdisciplinary Medicine, EarlyView.
TargetGen‐recurrent neural network (RNN), an advanced generative model, generated 28,708 unique and novel compounds, identifying SAK‐2970 as a potent antibiotic against drug‐resistant Staphylococcus aureus. Exhibiting strong biofilm inhibition, high therapeutic efficacy, and minimal systemic toxicity in vivo, SAK‐2970 highlights its safety and clinical
Shakeel Ahmad Khan, Adnan Shakoor, Sadia Kanwal   +2 more
wiley   +1 more source

A Person‐Centered Approach to Examining Out‐of‐School Participation Among Black Adolescents and Its Association With Racial and Ethnic Identity

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Positive racial and ethnic identity formation is associated with psychological well‐being, especially for Black adolescents. Parental socialization and school‐related factors are key influences that have been studied, but less is known about other factors in an adolescent's social ecology, such as out‐of‐school activities.
Maureen T. S. Burns, Amy M. Bohnert, Byron D. Brooks, Robin Hayen, Alexis Boe, Edith Chen   +5 more
wiley   +1 more source

Market Expansion and Business Stealing With Differentiated Products Using a Nested Logit

Journal of Applied Econometrics, EarlyView.
ABSTRACT In this paper, we use the widely adopted nested logit model to examine how introducing a new product into a market of highly substitutable, differentiated goods affects both market expansion and business stealing. Central to our analysis is the nesting parameter σ$$ \sigma $$, which captures the correlation in consumers' unobserved utilities ...
Christophe Bellégo, Andreea Enache
wiley   +1 more source

When Technology Meets Turbulence: The Impact of Digital Transformation and Policy Uncertainty on Audit Opinions

Journal of Corporate Accounting &Finance, EarlyView.
ABSTRACT This study investigates how Corporate Digital Transformation (CDT) influences audit opinions in Chinese A‐share‐listed non‐financial firms from 2011 to 2022, with a focus on the moderating role of Economic Policy Uncertainty (EPU). Results reveal an inverted U‐shaped relationship: moderate levels of CDT enhance audit outcomes through improved ...
He Min, Sultan Sikandar Mirza, Chengming Huang   +2 more
wiley   +1 more source

Physiologically Based Pharmacokinetic Modeling of Oxcarbazepine to Characterize Its Disposition in Children with Obesity

The Journal of Clinical Pharmacology, EarlyView.
Abstract Oxcarbazepine (OXC) is a second‐generation antiseizure medication, effective through its active metabolite, 10‐mono‐hydroxy derivative (MHD). OXC is used as adjunctive therapy for focal‐onset and primary generalized tonic–clonic seizures, with recommended dosing based on age and body weight.
Patricia D. Maglalang, Jaydeep Sinha, Victόria Etges Helfer, Andrea Edginton, Kanecia Zimmerman, Chi Dang Hornik, William J. Muller, Mobeen Rathore, Daniel K. Benjamin Jr., Jia‐Yuh Chen, Ravinder Anand, Daniel Gonzalez, the Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee   +12 more
wiley   +1 more source

Supporting Climate Science Research With 21st Century Technologies and a Virtual Student Conference for Upper Elementary to High School Students

, 2013
J. S. Malmberg, Keith Maull
openalex   +2 more sources