Results 51 to 60 of about 42,233 (256)

Implementasi Virtual Journey sebagai Media Belajar pada Pendidikan Anak Usia Dini

Jurnal Pelita PAUD, 2023
Perkembangan teknologi informasi memberikan peluang yang besar bagi pendidik anak usia dini mengembangan media belajar bagi keberlangsungan pembelajaran dengan baik.
Diah Pratiwi, Dian Hidayati
doaj   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

DESIGNING A PLAN FOR KEEPING A CONFERENCE IN COVID-19 CONTEXT [PDF]

Business Excellence and Management, 2020
The current social context, where we are facing problems like COVID-19 and climate changes, has created an environment where humans have to be innovative and find new ways to continue their lives showing respect for the rules, for the other people’s ...
Irina-Miruna RADU
doaj  

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Shifting away from the business-as-usual approach to research conferences

Biology Open, 2020
To combat the climate crisis, we need rapid, unprecedented social change. Scientists can play a lead role by signaling to society that we recognize the critical importance of redesigning our business-as-usual approach to research conferences. Traditional
Chelsie W. W. Counsell, Franziska Elmer, Judith C. Lang   +2 more
doaj   +1 more source

Decoupling Intrinsic Molecular Efficacy From Platform Effects: An Interpretable Machine Learning Framework for Unbiased Perovskite Passivator Discovery

Advanced Science, EarlyView.
This study establishes an interpretable machine learning framework that disentangles the intrinsic molecular efficacy of passivators from experimental platform effects—enabling unbiased, high‐throughput discovery of effective perovskite surface modifiers.
Jing Zhang, Ziyuan Li, Shan Gao, Zhen Zhu, Jing Wang, Xiangmei Duan   +5 more
wiley   +1 more source

Voices of conference attendees: how should future hybrid conferences be designed?

BMC Medical Education
Background With conference attendees having expressed preference for hybrid meeting formats (containing both in-person and virtual components), organisers are challenged to find the best combination of events for academic meetings.
Sai Sreenidhi Ram, Daniel Stricker, Carine Pannetier, Nathalie Tabin, Richard W Costello, Daiana Stolz, Kevin W Eva, Sören Huwendiek   +7 more
doaj   +1 more source

„AGMB 2021: Zuverlässig auch in stürmischen Zeiten”. Online-Jahrestagung der Arbeitsgemeinschaft für Medizinisches Bibliothekswesen (AGMB) e. V. vom 20. bis 22. September 2021

GMS Medizin – Bibliothek – Information, 2021
From 20 to 22 September 2021, the annual meeting of the German Medical Library Association took place purely online for the second time. The restrictions on public life due to the corona situation did not yet allow the conference to be held again as an ...
Härter, Dagmar, Reimann, Iris, Semmler-Schmetz, Martina, Wöckel, Claudia   +3 more
doaj   +1 more source

Unraveling the Power of Disorder: A Bioinspired Cuttlebone Structure With Superior Strength, Energy Absorption and Isotropy

Advanced Science, EarlyView.
Cuttlebone‐inspired architected metamaterials introduce controlled structural disorder to simultaneously enhance strength, energy absorption, and compressive stability. Tunable disorder suppresses shear anisotropy, outperforms periodic lattices, and establishes discrete randomness as a robust route to high‐performance lightweight mechanical ...
Zengqin Shi, Peng Jiang, Xiaoyan Zhu, Suyun Li, Wenqing Wang, Tian Zhao, Rujie He, Ying Li   +7 more
wiley   +1 more source

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

Advanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu, Yuhan Tang, Yingcui Chen, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Qiyuan Shi, Wenhui Zhao, Hui Pang   +8 more
wiley   +1 more source