Results 51 to 60 of about 658,337 (286)

$C^1$ Virtual Element Method on polyhedral meshes

open access: yesComputers & Mathematics with Applications, 2018
Computer & Mathematics with Applications (Jul 2019)
Beirao da Veiga L., Dassi F., Russo A.
openaire   +3 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

COMPARISON OF VIRTUAL FIELDS METHOD, PARALLEL NETWORK MATERIAL MODEL AND FINITE ELEMENT UPDATING FOR MATERIAL PARAMETER DETERMINATION

open access: yesActa Polytechnica CTU Proceedings, 2016
Extracting material parameters from test specimens is very intensive in terms of cost and time, especially for viscoelastic material models, where the parameters are dependent of time (frequency), temperature and environmental conditions.
Florian Dirisamer   +4 more
doaj   +1 more source

Lowest order Virtual Element approximation of magnetostatic problems

open access: yes, 2017
We give here a simplified presentation of the lowest order Serendipity Virtual Element method, and show its use for the numerical solution of linear magneto-static problems in three dimensions.
Brezzi, F.   +4 more
core   +1 more source

A virtual element method for the vibration problem of Kirchhoff plates [PDF]

open access: yes, 2017
The aim of this paper is to develop a virtual element method (VEM) for the vibration problem of thin plates on polygonal meshes. We consider a variational formulation relying only on the transverse displacement of the plate and propose an $H^2(\Omega ...
Mora, David   +2 more
core   +2 more sources

A virtual element method for transversely isotropic elasticity [PDF]

open access: yesComputational Mechanics, 2019
This work studies the approximation of plane problems concerning transversely isotropic elasticity, using a low-order Virtual Element Method (VEM), with a focus on near-incompressibility and near-inextensibility. Additionally, both homogeneous problems, in which the plane of isotropy is fixed; and non-homogeneous problems, in which the fibre direction ...
B. D. Reddy, D. van Huyssteen
openaire   +3 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

A Comparative Study of Numerical Methods for Topology Optimization: FEM, VEM, and SFEM on Unstructured Meshes

open access: yesRevista UIS Ingenierías
This work presents a comparative study of numerical methods for solving the elasticity equations in topology optimization problems. A computational framework written in MATLAB is used for solving topology optimization problems using different types of ...
Andrés José Rodríguez Torres   +2 more
doaj   +1 more source

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