Results 91 to 100 of about 4,619,619 (241)

Enhanced Virtual Inertia Controller for Microgrid Applications

open access: yes, 2023
Unlike Synchronous Generators (SGs), Virtual Synchronous Generators (VSGs) inertia is not fixed once it is manufactured and only has an upper limit defined by its energy storage components. In this paper, a novel Enhanced Virtual Inertia Controller (EVIC)
Ahmed Sheir, Vijay K. Sood
core   +1 more source

A Unified Hierarchical Multiscale Fusion Framework for Drug–Target Affinity Prediction: From Benchmark Performance to Nanomolar Inhibitor Discovery

open access: yesAdvanced Science, EarlyView.
A multimodal fusion framework integrating sequence, atomic, and fragment representations captures drug–target interactions across multiple scales. The model delivers strong predictive performance and enables efficient virtual screening. Applied to hematopoietic progenitor kinase 1 (HPK1), it identifies structurally diverse inhibitors with nanomolar ...
Shuo Liu   +7 more
wiley   +1 more source

Multi-objective configuration and evaluation of dynamic virtual inertia from DFIG based wind farm for frequency regulation

open access: yesInternational Journal of Electrical Power & Energy Systems
Modern power systems are gradually evolving into low-inertia systems due to the integration of high penetration of renewable energy and power electronic equipment.
Chao Jiang   +5 more
doaj   +1 more source

Comprehensive Coordinated Control Strategy of PMSG-Based Wind Turbine for Providing Frequency Regulation Services

open access: yesIEEE Access, 2019
A high proportion of wind energy in modern power system requires wind turbines (WTs) to provide frequency regulation services. In this context, this paper proposes a comprehensive coordinated control strategy of permanent magnet synchronous generator ...
Xueyang Zeng   +4 more
doaj   +1 more source

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

open access: yesAdvanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song   +7 more
wiley   +1 more source

A Preclinical Multifunctional Capsule Robot with Unified Diagnosis and Targeted Thermal Therapy for Gastrointestinal Diseases

open access: yesAdvanced Science, EarlyView.
A proof‐of‐concept multifunctional capsule robot integrates diagnostic imaging, magnetic navigation, wireless power transfer, and targeted thermotherapy for gastrointestinal applications. Magnetically guided positioning and stable wireless power enable localized thermal ablation, achieving controlled heating and high cell mortality in vitro.
Heng Zhang   +7 more
wiley   +1 more source

Similarity‐Enhanced Representation Learning of Non‐Canonical Amino Acids for Therapeutic Peptide Modeling

open access: yesAdvanced Science, EarlyView.
Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu   +8 more
wiley   +1 more source

Virtual Inertia Planning for Enhancing Grid Stability in Low‐Inertia Systems

open access: yesIET Energy Systems Integration
ABSTRACT The global power grid is undergoing a significant transition with the increasing integration of renewable energy sources (RESs). This shift, characterised by a decline in conventional synchronous generators and a rise in inverter‐based RESs, has resulted in reduced grid inertia, posing substantial challenges to frequency ...
S. Saha   +3 more
openaire   +1 more source

Coordinated control of grid-following and grid-forming energy storage for virtual inertia response considering frequency modal characteristics

open access: yesInternational Journal of Electrical Power & Energy Systems
Grid-following energy storage (GFL-ES) and grid-forming energy storage (GFM-ES) will coexist for a certain period into the future as one of the frequency regulation resources in low-inertia power systems.
Hengning Yu   +5 more
doaj   +1 more source

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li   +9 more
wiley   +1 more source

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