Results 111 to 120 of about 4,619,619 (241)

Optimizing Cancer Vaccinations Using a Physiologically‐Based Pharmacokinetic/Pharmacodynamic (PBPK/PD) Model

open access: yesAdvanced Science, EarlyView.
Where and when should a cancer vaccine be administered? A whole‐body PBPK model demonstrates that systemic immune transport critically determines vaccination efficacy. By simulating how organ‐specific immune interactions influence treatment response, the study provides a quantitative framework for optimizing cancer vaccination strategies.
Mohammad R. Nikmaneshi   +2 more
wiley   +1 more source

Demo 02-15 Tablecloth Jerk

open access: yes, 2001
This demonstration shows the old magician's trick of pulling a silk tablecloth out from under a dining room setting without upsetting any of the items on the tablecloth.

core  

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

open access: yesAdvanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng   +17 more
wiley   +1 more source

Data‐Driven and Physics‐Informed Modeling Perspectives for Soft Manipulators: From SINDy to Hybrid Intelligence

open access: yesAdvanced Science, EarlyView.
This Perspective charts the modeling landscape for soft manipulators, spanning sparse system identification, neural dynamics, physics‐informed models and hybrid intelligence. We examine how physics, data, sensing, adaptation and control can assume complementary roles within this landscape, and provide a framework for selecting modeling approaches ...
Wenbo Hui   +4 more
wiley   +1 more source

Chemical Inhibition of Pyocyanin Biosynthesis Attenuates Virulence of Pseudomonas aeruginosa

open access: yesAngewandte Chemie, EarlyView.
Anti‐virulence strategies disarm pathogens rather than killing them directly. A β‐lactone reduces pyocyanin production without affecting growth. Chemical proteomics identified PqsC as the primary target via binding to Cys129. Crystallography revealed the binding mode, and SAR yielded a chloroacetamide inhibitor with improved enzymatic potency and anti ...
Wei Ding   +3 more
wiley   +2 more sources

A fuzzy-based dual-port virtual inertia controller for enhancing dynamic performance in hybrid microgrids

open access: yesInternational Journal of Electrical Power & Energy Systems
In hybrid microgrids (HMGs), reduced deviations and global power sharing can be expected by utilizing the interlinking converters (ILCs). However, the HMGs struggle to manage an optimal inertial response by interconnecting multiple AC/DC microgrids with ...
Yan Du   +4 more
doaj   +1 more source

Virtual Inertia Control of Microgrid Consisting of Low Inertia Resources

open access: yesمهندسی مخابرات جنوب
In this paper, an adaptive concept of virtual generator based controller for dynamic stability of microgrids consisting of low inertia resources. For this purpose, considering a set of energy storage systems dispatched in the network, a controlled islanding scheme  is provided to dynamically control the microgrid frequency.
Sahar Roudi   +3 more
openaire   +1 more source

MagGami: An Electromagnetic Origami Actuator With High Stiffness‐Switching Density for Lightweight Joint‐Space Wearable Haptics

open access: yesAdvanced Science, EarlyView.
Concept of the MagGami‐based joint‐space haptic glove. a) Comparison between Cartesian‐space fingertip force feedback and distributed joint‐space torque feedback, highlighting the limitations of representative motor‐driven, pneumatic, and smart material‐based haptic actuators.
Tianhao Jin   +9 more
wiley   +1 more source

From Artificial to Embodied and Physical Intelligence in Smart Manufacturing

open access: yesAdvanced Science, EarlyView.
Smart manufacturing is reframed through complementary artificial, embodied, and physical intelligence, spanning computational reasoning, perception‐action coupling, and material‐level adaptation. Their integration across design, fabrication, operation, and maintenance reveals how intelligence can be co‐designed across algorithms, embodied agents, and ...
Kang Wang   +9 more
wiley   +1 more source

Virtual Inertia Parameter Feasible Region Based High-frequency Oscillation Suppression of DC Microgrid

open access: yesZhongguo dianli
Addressing the issue of high-frequency oscillation instability in DC microgrids caused by unreasonable virtual inertia control parameters, a low-pass filter equivalent modeling approach is proposed.
Rui WANG   +5 more
doaj   +1 more source

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