Results 161 to 170 of about 8,376 (257)

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

A novel selective stabilizer of the ryanodine receptor 2 prevents stress‐induced ventricular arrhythmias without impairing cardiac function

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Aberrant activation of type 2 ryanodine receptors (RyR2) causes lethal arrhythmias, such as catecholaminergic polymorphic ventricular tachycardia (CPVT). Developing drugs that suppress RyR2 hyperactivation may be key to novel arrhythmia treatments.
Nagomi Kurebayashi   +29 more
wiley   +1 more source

MaX4Zero: Masked Extended Attention for Zero‐Shot Virtual Try‐On In The Wild

open access: yesComputer Graphics Forum, EarlyView.
Max4Zero is a zero‐shot, training‐free virtual try‐on method that leverages diffusion priors and extended attention for accurate garment transfer. By warping reference garments and mitigating texture sticking, it achieves superior fidelity, garment preservation and identity consistency over state‐of‐the‐art methods without additional training ...
Nadav Orzech   +4 more
wiley   +1 more source

A Semi‐Analytical Energy Model for Particle‐Based Fluid Simulation Involving Complex Moving Boundaries

open access: yesComputer Graphics Forum, EarlyView.
Abstract While semi‐analytical boundary handling techniques have proven effective for modeling particle‐based fluid‐solid interactions, they can become unstable when applied to mesh boundaries undergoing dynamic motion or featuring complex, sharp geometries.
Junyuan Liu   +5 more
wiley   +1 more source

Interpolated Adaptive Linear Reduced Order Modeling for Deformation Dynamics

open access: yesComputer Graphics Forum, EarlyView.
Abstract Linear reduced‐order modeling (ROM) is widely used for efficient simulation of deformation dynamics, but its accuracy is often limited by the fixed linearization of the reduced mapping. We propose a new adaptive strategy for linear ROM that allows the reduced mapping to vary dynamically in response to the evolving deformation state ...
Y. Tao, M. Chiaramonte, P. Fernandez
wiley   +1 more source

Implementing a model of integrated CKD management between primary and secondary care. [PDF]

open access: yesClin Kidney J
Jones P   +6 more
europepmc   +1 more source

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