Results 161 to 170 of about 59,693 (314)

Large‐Scale Machine Learning to Screen for Small‐Molecule Senolytics

Advanced Intelligent Discovery, EarlyView.
A consistent workflow underpins all experiments in this study. A dedicated model‐selection dataset first identifies optimal hyperparameters for each algorithm. Models are then trained and rigorously evaluated on independent sets of molecules using the senolytic ratio SR. Comprehensive hyperparameter exploration across SMILES representations, task types,
Alexis Dougha, Jesus Gil, Pedro J. Ballester   +2 more
wiley   +1 more source

Virtual Library Services for a Virtual University : User-Oriented Virtual Sites in an Open Library

, 2001
L'arribada de les tecnologies de la informació, i el sempre creixement i el seu ús generalitzat, ha permès que aparegui una nova situació que, alhora, ha originat - de fet, que ha precipitat - una sèrie de canvis de gran importància en tots els nivells, però especialment en els nivells socials, econòmics i culturals.
Pérez Alarcón, Adoració, Enrech Larrea, Marta   +1 more
openaire   +1 more source

Accelerating Discovery of Organic Molecular Crystals via Materials Informatics and Autonomous Experiments

Advanced Intelligent Discovery, EarlyView.
Materials informatics and autonomous experimentation are transforming the discovery of organic molecular crystals. This review presents an integrated molecule–crystal–function–optimization workflow combining machine learning, crystal structure prediction, and Bayesian optimization with robotic platforms.
Takuya Taniguchi, Kazuki Ishizaki, Ryo Fukasawa   +2 more
wiley   +1 more source

Informatics-Based Design of Virtual Libraries of Polymer Nano-Composites. [PDF]

Int J Mol Sci
Liu Q, Broderick SR.
europepmc   +1 more source

The Adoption of Information and Communication Technology (ICT) in the University Libraries of Bangladesh: An Exploratory Study

, 2011
This study aims to explore the extent of adoption of information and communication technology (ICT) in the university libraries of Bangladesh. The study discusses the present conditions of using ICT by the public and private university libraries in ...
Munshi, Nasiruddin, Sayeed, Abu, Siddike, Abul Kalam   +2 more
core  

Large Language Model‐Based Chatbots in Higher Education

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
The use of large language models (LLMs) in higher education can facilitate personalized learning experiences, advance asynchronized learning, and support instructors, students, and researchers across diverse fields. The development of regulations and guidelines that address ethical and legal issues is essential to ensure safe and responsible adaptation
Defne Yigci, Merve Eryilmaz, Ail K. Yetisen, Savas Tasoglu, Aydogan Ozcan   +4 more
wiley   +1 more source

Light‐Controlled Modulation of 15‐Lipoxygenase‐1 Regulates Intestinal Inflammatory Signaling

Angewandte Chemie, EarlyView.
The developed target‐guided strategy enables the rational design of diazo‐based photoswitchable inhibitors of 15‐lipoxygenase‐1. Distinct molecular architectures program opposite light‐dependent activity, allowing on‐demand control of enzyme inhibition.
Anastasia Louka, Eirini‐Eleni Kalaitzaki, Athanasios Panousis, Sotirios Bonoras, Charalampos Livas, George Froudakis, Ioannis Drygiannakis, Athina Damianaki, George Kolios, Vassilis Valatas, Nikolaos Eleftheriadis   +10 more
wiley   +2 more sources

High-Affinity Peptides for Target Protein Screened in Ultralarge Virtual Libraries. [PDF]

ACS Cent Sci
Xue B, Li R, Cheng Z, Zhou X.
europepmc   +1 more source

Calibration‐Free Electromyography Motor Intent Decoding Using Large‐Scale Supervised Pretraining

Advanced Intelligent Systems, EarlyView.
Calibration‐free electromyography motor intent decoding is enabled through large‐scale supervised pretraining across heterogeneous datasets. A Spatially Aware Feature‐learning Transformer processes variable channel counts and electrode geometries, allowing transfer across users and recording setups. On a held‐out benchmark, fine‐tuned cross‐user models
Alexander E. Olsson, Nebojša Maleševic, Anders Björkman, Christian Antfolk   +3 more
wiley   +1 more source

Correlation of protein binding pocket properties with hits' chemistries used in generation of ultra-large virtual libraries. [PDF]

J Comput Aided Mol Des
Song RX, Nicklaus MC, Tarasova NI.
europepmc   +1 more source