Results 121 to 130 of about 14,235 (282)

A Virtual Network Embedding Algorithm Based on Graph Theory

open access: yes, 2013
Part 1: Session 1: Parallel Programming and AlgorithmsInternational audienceNetwork virtualization is becoming a promising way of removing the inherent ossification of the Internet, and has been steadily attracting more and more researchers’ attention ...
Wang, Songyang   +9 more
core   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

open access: yesAdvanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang   +14 more
wiley   +1 more source

Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model

open access: yesAdvanced Science, EarlyView.
A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen   +15 more
wiley   +1 more source

Survey of virtual network embedding problem

open access: yesTongxin xuebao, 2011
Related research work of virtual networks(VN) embedding was surveyed,and both of the advantages and dis-advantages in the key technologies of related research work were analyzed.The possible future research directions were also discussed as references ...
CHENG Xiang   +3 more
doaj   +2 more sources

Evaluation study of virtual network embedding for short-lived virtual networks

open access: yes, 2016
Cloud services are currently being extensively used for server hosting, data storage, scientific and research purposes. Virtualization technology is an essential element for these services.
Palagummi, Mydhili
core  

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

open access: yesAdvanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang   +6 more
wiley   +1 more source

A Decomposition-based Architecture for Distributed Virtual Network Embedding

open access: yes, 2014
Network protocols have historically been developed on an ad-hoc basis, and cloud computing is no exception. A fundamental management protocol, not yet standardized, that cloud providers need to run to support wide-area virtual network services is the ...
Flavio Esposito, Ibrahim Matta
core   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

open access: yesAdvanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang   +11 more
wiley   +1 more source

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