Results 211 to 220 of about 1,661,704 (376)

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

Advanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen, Jindi Huang, Cong Liu, Shipeng Zhang, Xinze Li, Zhang Zhang, Tie‐Gen Chen, Ling Wang   +7 more
wiley   +1 more source

Energy-Aware adaptive virtualization and migration protocol for green IoT wireless sensor networks. [PDF]

Sci Rep
Liu Y, Li Y, Ge N.
europepmc   +1 more source

Cross-VM Cache Timing Attacks on Virtualized Network Functions

, 2019
Youngjoo Shin
openalex   +2 more sources

Joint Orchestration of Cloud-Based Microservices and Virtual Network Functions [PDF]

, 2018
Hadi Razzaghi Kouchaksaraei, Holger Karl
openalex   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Fuzzy based priority aware task scheduling optimization for mobile edge computing environments. [PDF]

Sci Rep
Lin P.
europepmc   +1 more source

Allocation of Virtual Firewall Functions in NFV-Based Networks with Minimum Network Cost

, 2019
Shin-ichi Kuribayashi
openalex   +2 more sources

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

Advanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang, Yifan Wu, Hao Luo, Minglong Liang, Yihang Zhou, Cheng Chen, Chris Liu, Jun Zhang, Yang Zhang   +8 more
wiley   +1 more source

Virtual Reality-Based Cognitive and Physical Interventions in Cognitive Impairment: A Network Meta-Analysis of Immersion Level Effects. [PDF]

Behav Sci (Basel)
Li W, Gao W, Lin X.
europepmc   +1 more source

Monitoring and identifying bottlenecks in virtual network functions service chains

, 2019
Ricardo J. Pfitscher
openalex   +1 more source