Results 241 to 250 of about 5,579,484 (341)

Towards user-centered interactive medical image segmentation in VR with an assistive AI agent. [PDF]

Virtual Real
Spiegler P, Harirpoush A, Xiao Y.
europepmc   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

A novel approach to promote upper-limb motor recovery in stroke survivors using assistive myoelectric control and adaptive visual feedback in virtual reality. [PDF]

Front Bioeng Biotechnol
Nocilli M, d'Avella A, Berger DJ.
europepmc   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Assessment of early gastric cancer visibility in deep-learning-based virtual indigo carmine chromoendoscopy (with video). [PDF]

Endosc Int Open
Takasu A, Suzuki S, Monno Y, Minai M, Hirasawa T, Yamamoto H, Ishibashi F, Nishizawa T, Okutomi M, Tada T.   +9 more
europepmc   +1 more source

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

Advanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang, Yifan Wu, Hao Luo, Minglong Liang, Yihang Zhou, Cheng Chen, Chris Liu, Jun Zhang, Yang Zhang   +8 more
wiley   +1 more source

Virtual Vernier Effect-Enabled Parallel Dual-Cavity Sensor for Temperature and Humidity Synchronization. [PDF]

Nanomaterials (Basel)
Li Y, Mu X, Yang Y, Xia H, Zhang Y, Mo C, Huang Z, Li Y, Li F.   +8 more
europepmc   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

The discovery of monoamine oxidase inhibitors: virtual screening and in vitro inhibition potencies. [PDF]

J Comput Aided Mol Des
Shaw M, Petzer A, Crous C, Cloete TT, Petzer JP.   +4 more
europepmc   +1 more source

Correction: The impact of virtual reality on student engagement in the classroom-a critical review of the literature. [PDF]

Front Psychol
Lin XP, Li BB, Yao ZN, Yang Z, Zhang M.
europepmc   +1 more source