Results 61 to 70 of about 21,831 (281)

Uso de sistemas basados en escáner 3D para digitalización y estudio del patrimonio arqueológico

Virtual Archaeology Review, 2010
3D scanners are becoming useful tools in many fields like civil engineering, heritage restoration or archaeology. Speed, accuracy and security are several key features of these systems. The data generated by a 3D scanner can be used in many ways: since a
Manuel J. González Muñoz, Antonio J. Rueda Ruiz, Rafael J. Segura Sánchez, Carlos J. Ogáyar Anguita, Antonio Esteban Hoyas, Javier Lara   +5 more
doaj   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Dynamic virtual network restoration with optimal standby virtual router selection [PDF]

NOMS 2016 - 2016 IEEE/IFIP Network Operations and Management Symposium, 2016
Fault-tolerance in a virtualized networking environment (VNE) requires additional efforts to provide the survivability against failures on either virtual networks (VNs) or the underlying substrate network. In this dissertation, we design a software-defined resilient VNE using a hybrid scheme of protection and restoration, where for each VN, a set of ...
Xuan Liu 0002, Deep Medhi
openaire   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou, Yifei Zhu, Cheng Zeng, Jinlu Han, Huiying Huang, Doudou Li, Mingxi Lin, Yizi Jin, Qin Guo, Yuxin Yan, Xinhui Mao, Yifei Zhou, Jian Zhang   +12 more
wiley   +1 more source

Virtual Dunhuang Mural Restoration System in Collaborative Network Environment

, 2000
This paper introduces a virtual Dunhuang mural restoration system in collaborative network environment. It describes the style of Dunhuang mural, analyzes the reasons of mural spoilage, and presents the necessity to develop a collaborative mural ...
Lu, Dongming, Pan, Yunhe, Li, Xiangyang
core   +1 more source

Physics‐Embedded Neural Network: A Novel Approach to Design Polymeric Materials

Advanced Science, EarlyView.
Traditional black‐box models for polymer mechanics rely solely on data and lack physical interpretability. This work presents a physics‐embedded neural network (PENN) that integrates constitutive equations into machine learning. The approach ensures reliable stress predictions, provides interpretable parameters, and enables performance‐driven, inverse ...
Siqi Zhan, Hengheng Zhao, Haotian Wang, Zhanjie Liu, Qian Li, Weifeng Zhang, Qingsong Zhao, Liqun Zhang, Jun Liu   +8 more
wiley   +1 more source

Reinnervation of Muscle Targets Enhances the Separability of Motor Unit Signals Following Peripheral Nerve Transfers

Advanced Science, EarlyView.
Injured or cut peripheral nerves can be surgically rerouted to reinnervate new muscle targets. This study demonstrates reinnervated muscles exhibit enhanced separability between individual motor unit signals, which can simplify signal recording and decomposition. These findings highlight the potential of reinnervated muscle to serve as a key biological
Kiara N Quinn, Siyu Wang, Lang Qin, Alessandro Ascani Orsini, Kenzi Griffith, Rachana Suresh, Fausto Kang, Pierce L Perkins, Neha Joshi, Alexis L Lowe, Sami Tuffaha, Nitish V Thakor   +11 more
wiley   +1 more source

Intelligent Recognition and Restoration of Mural Damage Based on DeepLabv3 and Stable Diffusion

Buildings
Murals are not merely independent visual artworks. Rather, they are an integral part of architectural heritage, directly attached to buildings’ structural elements, such as brick walls and vaults.
Chong Rong, Dashuai Yang, Wenkai Tian, Yi Tao, Qiuwei Wang, Peng Wang   +5 more
doaj   +1 more source

Digital protection and virtual restoration of cultural relics based on multimodal data

Open Computer Science
To address issues such as information loss and insufficient restoration accuracy in the process of cultural relic protection and restoration, this study proposes a digital protection and virtual restoration method for cultural relics that integrates ...
Guo Wenjie
doaj   +1 more source