Results 311 to 320 of about 2,795,372 (389)

MGPT: A Multi‐task Graph Prompt Learning Framework for Drug Discovery

Advanced Science, EarlyView.
MGPT is a unified multi‐task graph prompt learning model providing generalizable and robust graph representations for few‐shot drug association prediction. MGPT demonstrates the ability of seamless task switching and outperforms competitive approaches in few‐shot scenarios.
Yang Li, Youhan Sun, Xinyu Qin, Xin Gao, Guohua Wang   +4 more
wiley   +1 more source

Recent Advances of Microcapsule‐based Intelligent Coatings: From Bioinspired Designs, Material Selections, to Potential Applications

Advanced Science, EarlyView.
Microcapsule‐based intelligent coatings (MICs) have shown great potential in the fields of biomedicine, smart buildings, marine protection, and aerospace. However, they currently face challenges in the integration of coating functions and applications in complex systems.
Yue Zhao, Xiaopeng Cheng, Ran Zhao, Xipeng Li, Jingxin Meng, Shutao Wang   +5 more
wiley   +1 more source

Normalized Protein-Ligand Distance Likelihood Score for End-to-End Blind Docking and Virtual Screening. [PDF]

J Chem Inf Model
Xia S, Gu Y, Zhang Y.
europepmc   +1 more source

Vertical GaN‐On‐GaN Micro‐LEDs for Near‐Eye Displays

Advanced Science, EarlyView.
This work advances micro‐light‐emitting diode (micro‐LED) technology using GaN‐on‐GaN homoepitaxial platforms for low defects. Fluorine ion implantation replaces plasma etching for pixel isolation, reducing series resistance and enhancing optical quality. Vertical architectures enable dense integration.
Zichun Li, Yibo Liu, Haonan Jiang, Feng Feng, Jingyang Zhang, Shan Huang, Fion Yeung, Manchun Tseng, Man Wong, Hoi Sing Kwok, Zhaojun Liu   +10 more
wiley   +1 more source

Deep learning pipeline for accelerating virtual screening in drug discovery. [PDF]

Sci Rep
Noor F, Junaid M, Almalki AH, Almaghrabi M, Ghazanfar S, Tahir Ul Qamar M.   +5 more
europepmc   +1 more source

PLAUR+ Neutrophils Drive Anti‐PD‐1 Therapy Resistance in Patients with Hepatocellular Carcinoma by Shaping an Immunosuppressive Microenvironment

Advanced Science, EarlyView.
The present study reveals that PLAUR+ neutrophils are enriched in immunotherapy non‐responders and correlate with poor prognosis. PLAUR+ neutrophils dictate immunotherapy resistance in hepatocellular carcinoma by forming an immunosuppressive tumor microenvironment characterized by CD8+ T cell exclusion and macrophage‐dependent immune suppression.
Shaoqing Liu, Yanzhao Zhou, Gaoxiang Li, Bingwen Zhu, Fang Wu, Jinxue Zhou, Xiaobing Chen, Bo Qin, Yanxia Gao, Fazhan Wang, Yong Jiang, Wenxin Xu   +11 more
wiley   +1 more source

Virtual screening combined with molecular docking for the !identification of new anti-adipogenic compounds. [PDF]

Sci Prog
Mandujano-Lázaro G, Torres-Rojas MF, Ramírez-Moreno E, Marchat LA.   +3 more
europepmc   +1 more source

Advanced Brain‐on‐a‐Chip for Wetware Computing: A Review

Advanced Science, EarlyView.
Exploring Low‐Power, Beyond‐Silicon‐Computing Bio‐Computing: Brain‐on‐a‐Chip Technology. This article reviews the applications of Brain‐on‐a‐Chip in Wetware Computing, including in vitro‐cultured brain organoids, microelectrode arrays, electrophysiological interfaces, and microfluidic platforms, as well as data processing methods. It also looks forward
Shangchen Li, Yaoyao Liu, Sihan Hua, Yu Wang, Shutong Sun, Longhui Jiang, Chengji Lu, Juntao Liu, Huaizhang Shi, Pei Wu, Xinxia Cai, Jinping Luo   +11 more
wiley   +1 more source

Identification of a Potent CDK8 Inhibitor Using Structure-Based Virtual Screening. [PDF]

J Chem Inf Model
Lin TE, Chou CH, Wu YW, Sung TY, Hsu JY, Yen SC, Hsieh JH, Chang YW, Pan SL, Huang WJ, Hsu KC, Yang CR.   +11 more
europepmc   +1 more source

Artificial Intelligence Is Stereotypically Linked More with Socially Dominant Groups in Natural Language

Advanced Science, EarlyView.
AI is not seen through an unbiased lens. People tend to stereotype AI as competent and link it with socially advantaged groups—such as men, the wealthy, the young, and prestigious occupations—raising concerns that such perceptions may deepen existing social divides rather than bridge them.
Zixi Wang, Haodong Xia, Han Wu Shuang Bao, Yiming Jing, Ruolei Gu   +4 more
wiley   +1 more source