Results 221 to 230 of about 709,208 (298)

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
ABSTRACT This special issue marking the University of Bath's 60th anniversary offers an opportunity to reflect on nearly a decade of research into the evolution of gene regulatory networks (GRNs) from members of the lab and elsewhere. Our goal is to understand how GRNs rewire and how new transcription factor (TF) functions evolve. Using an experimental
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Virtual simulation for flow-diverter selection and sizing in the endovascular treatment of intracranial aneurysms: A systematic review and meta-analysis. [PDF]

Interv Neuroradiol
Ferreira C, Ferreira MY, Bertani R, Palavani LB, Borges PG, Günkan A, Müller GC, Maia HG, Semione G, Batista S, Lepine HL, Zumofen D, Stark K, Hanel RA, Gordon D, Serulle Y, Langer D.   +16 more
europepmc   +1 more source

Deformation Driven Suction Cups: A Mechanics‐Based Approach to Wearable Electronics

Advanced Science, EarlyView.
Deformation‐driven suction cups enable robust, reversible adhesion of wearable electronics to human skin spanning wide mechanical compliance, without adhesives or tight straps. By integrating mechanics modeling, experiments, and contact mechanics theory, this work reveals how cup geometry, substrate compliance, and interfacial adhesion govern suction ...
Seola Lee, Andrew Akerson, Roham Pardakhtim, Ehsan Hajiesmaili, Kevin Rhodes, Zidong Li, Andrew Stanley, Amirhossein Amini, Daniele Piazza, Chiara Daraio, Tianshu Liu   +10 more
wiley   +1 more source

Responding to Interprofessional Microaggressions: Bystander Training-A Virtual Simulation Curriculum for Internal Medicine Residents. [PDF]

MedEdPORTAL
Govindraj R, Binda DD, Harris AC, Ananthakrishnan S, McGrath ME, Kuohung W, Hsu TY, Siegel J, Yadavalli G.   +8 more
europepmc   +1 more source

Systematically Engineering for Efficient Production of 3‐Methyl‐1‐Butanol in Escherichia coli

Advanced Science, EarlyView.
An integrated metabolic engineering strategy was established for high‐level 3‐methyl‐1‐butanol biosynthesis in Escherichia coli. Molecular dynamics‐guided semi‐rational engineering of dihydroxyacid dehydratase uncovered and relieved key catalytic bottlenecks, while adaptive laboratory evolution enhanced strain robustness.
Nanfei Geng, Hao Liu, Haolin Han, Meng Meng, Shaojie Wang, Tianwei Tan, Haijia Su   +6 more
wiley   +1 more source

Accelerated Discovery of Topological Conductors for Nanoscale Interconnects

Advanced Science, EarlyView.
Copper interconnects exhibit a sharp increase in resistivity at ultra‐scaled dimensions, threatening continued miniaturization of integrated circuits. The gapless surface states of topological semimetals provide conduction channels resistant to localization.
Alexander C. Tyner, William Rogers, Po‐Hsin Shih, Yi‐Hsin Tu, Gengchiau Liang, Hsin Lin, Ching‐Tzu Chen, James M. Rondinelli   +7 more
wiley   +1 more source

Enhancing Student Comprehension of Glucose Metabolism Visualization Through Virtual Simulation Platform: An Educational Approach. [PDF]

Pharmacol Res Perspect
Ge L, Feng T, Cao S, Yin H, Zhang Y, Pan J, Chen W, Cheng K, Wang L.   +8 more
europepmc   +1 more source

Phase‐Engineered Non‐Degenerate Sliding Ferroelectricity Enables Tunable Photovoltaics in Monolayer Janus In2S2Se

Advanced Science, EarlyView.
The meticulously phase‐engineered non‐degenerate sliding ferroelectricities in monolayer In2S2Se, along with their tunable impacts on photovoltaic performances, introduce innovative perspectives for the future design and optimization of 2D advanced photovoltaic devices.
Yixuan Li, Qiang Wang, Keying Han, Yitong Liang, Kai Kong, Yan Liang, Thomas Frauenheim, Xingshuai Lv, Defeng Guo, Bin Wang   +9 more
wiley   +1 more source

Decoding Proton‐Coupled Electron Transfer Mechanism of Nicotine for Multi‐Scenario Portable Electrochemical Sensing

Advanced Science, EarlyView.
A key challenge in nicotine electroanalysis is the unresolved complexity of its interface process, which directly determines sensor metrics. Herein, the proton‐coupled electron transfer mechanism of nicotine is decoded for multi‐scenario portable electrochemical sensing.
Yi Peng, Qinyi Cao, Qianyu Shen, Yuhang Zhang, Shiyu Hu, Hongdou Yi, Qian Liu, Lihui Ou, Qiang Li, Zhaohong Su   +9 more
wiley   +1 more source

Teaching high quality paediatric basic life support to laypeople: The development and evaluation of a virtual simulation game. [PDF]

Resusc Plus
Boggs S, McNally JD, O'Hearn K, Del Bel M, Armstrong J, Newhook D, Lobos AT.   +6 more
europepmc   +1 more source