Results 241 to 250 of about 776,989 (303)

Application and development of artificial intelligence and immersive technologies in dental education: a scoping review. [PDF]

BMC Med Educ
Huang S, Qu Y, Sun Y, Chen S, Gu L.
europepmc   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Evaluation of a virtual simulation system for root canal irrigation training in preclinical dental education. [PDF]

BMC Med Educ
Yue X, Nie S, Dai Y, Sun J, Xu L, Shen J.   +5 more
europepmc   +1 more source

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Virtual patient simulation to enhance medical students' clinical communication and decision-making skills: a pilot study. [PDF]

BMC Med Educ
Dávidovics A, Dávidovics K, Hillebrand P, Rendeki S, Németh T.   +4 more
europepmc   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

Introducing a Smartphone Tele-Objective Structured Clinical Examination to Support High-Stakes Competency Decisions: A Quasi-Experimental Study and Curricular Implications. [PDF]

J Med Educ Curric Dev
Wang X, Du J, Luo B, Chen L, Chen H, Jiang S, Sun W, Zhou L, Konge L, Huang H, Ding Q.   +10 more
europepmc   +1 more source

Educational Interventions to Prepare Undergraduate Students for Out-of-Hours Practice as a Newly Qualified Doctor in the United Kingdom: A Scoping Review. [PDF]

Clin Teach
Gordon A, Parkinson M, Watts R, El-Badawi K, Dawson E, Chiktara R, Burns L, Brennan N.   +7 more
europepmc   +1 more source

Engineering student wellbeing in hybrid learning environments post-COVID-19: a call for targeted mental health interventions. [PDF]

Front Psychol
Firmante MCM.
europepmc   +1 more source

Development of a multi-skill, haptic-supported virtual reality simulation for first-year nursing students: a pilot study. [PDF]

BMC Nurs
Bozkurt R, Doğu Ö, Çit G, Ayar K, Öz C.   +4 more
europepmc   +1 more source