Results 131 to 140 of about 30,698 (299)

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

open access: yesAdvanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian   +13 more
wiley   +1 more source

STUDY ON DAMAGE ASSESSMENT FOR BEAM TYPE STRUCTURES BY VIRTUAL LOAD METHOD

open access: yesJixie qiangdu, 2019
The virtual load method is studied in this paper for damage assessment of beam type structures. The main advantage of this technique is that damage assessment can be accomplished by using only the vibration modes of the current structure.
LI CuiHong   +3 more
doaj  

Evaluating transient stability of power systems by stability-preserving transfer of state vectors into domain of attraction of a state-reduction model

open access: yesInternational Journal of Electrical Power & Energy Systems
Evaluating the transient stability of power systems based on the analytical domain of attraction (DA) is a challenging problem due to the difficulty in finding an optimal estimate of the boundary of DA for higher dimensional nonlinear systems. This paper
Yang Liu   +6 more
doaj   +1 more source

Construction of Sabatier Volcanoes for CO2 Hydrogenation to C1‐2 Oxygenates Using Data‐Efficient Machine Learning

open access: yesAdvanced Science, EarlyView.
A new data‐efficient framework combining DFT calculations, a neural network model, and automated graph analysis of catalytic reaction networks is proposed and applied to CO2 hydrogenation on transition metal nanoparticles. The analysis shows how efficient C2 oxygenate production requires a balance between CHx formation, C–C coupling, protonation, and ...
Mikhail V. Polynski, Sergey M. Kozlov
wiley   +1 more source

Machine Learning‐Assisted KCl‐CaCl2‐LiCl Electrolyte Design for Low‐Temperature, High‐Performance Calcium‐Based Liquid Metal Batteries

open access: yesAdvanced Science, EarlyView.
A machine learning‐assisted framework optimizes the KCl‐CaCl2‐LiCl ternary electrolyte. The optimized 13:35:52 mol% composition enables Ca‐based liquid metal batteries to operate stably at 480 °C, with >99.5% coulombic efficiency, ultralow self‐discharge, and excellent cycling stability, advancing low‐temperature large‐scale energy storage.
Xinglin Zhou   +3 more
wiley   +1 more source

DOA estimation algorithm for non-circular signal by a large-spacing array with auxiliary element

open access: yesScientific Reports
In this paper, a direction of arrival (DOA) estimation algorithm for non-circular signal by a large-spacing uniform array with an auxiliary element has been presented.
Sheng Liu, Jing Zhao, Decheng Wu
doaj   +1 more source

Synergistic Integration of Artificial Merkel Disc and Meissner Corpuscle via Dermal Papillary Structures for Mechanically Filtered Multimodal Tactile Sensing

open access: yesAdvanced Science, EarlyView.
A multimodal tactile sensor module that mimics the spatial arrangement and function of Merkel discs and Meissner corpuscles within the human papillary structure operates in a self‐powered manner, responding to both dynamic and static stimuli, achieving tactile perception more similar to human skin.
Jaehyeong Kim   +4 more
wiley   +1 more source

Virtual-vector-based space vector pulse width modulation of the DC-AC multilevel-clamped multilevel converter (MLC2)

open access: yes
This work presents the development of the space vector pulse width modulation (SVPWM) of a new multi-level converter topology. First, the proposed converter and its natural space vector diagram are presented.
Muñoz Aguilar, Raúl Santiago   +4 more
core  

Low-complexity virtual-vector-based FCS-MPC with unaffected neutral-point voltage for three-phase T-type inverters

open access: yes
This article presents a new finite control set model predictive control (FCS-MPC) algorithm for three-phase (3P) T-type voltage source inverters. The proposed algorithm incorporates a vector combination technique to generate a total of 51 virtual vectors
Chen, Rong   +8 more
core   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

open access: yesAdvanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu   +9 more
wiley   +1 more source

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