Results 191 to 200 of about 2,422 (256)

Privacy Protection Optimization Method for Cloud Platforms Based on Federated Learning and Homomorphic Encryption. [PDF]

Sensors (Basel)
Wang J, Wang Y.
europepmc   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

The Construction of a Stream Service Application with DeepStream and Simple Realtime Server Using Containerization for Edge Computing. [PDF]

Sensors (Basel)
Shih WC, Wang ZY, Kristiani E, Hsieh YJ, Sung YH, Li CH, Yang CT.   +6 more
europepmc   +1 more source

AI‐Enabled Precision Dosing in Pediatrics: Enhancing Model‐Informed Decision Making

Clinical Pharmacology &Therapeutics, EarlyView.
Ensuring safe and effective pharmacotherapy for children remains a central challenge in clinical pharmacology, yet rapid advances in AI have not translated into clinical practice. This Perspective highlights how AI‐enabled approaches can enhance model‐informed decision making for precision dosing.
Kei Irie, Tomoyuki Mizuno
wiley   +1 more source

Behavioral science labs: How to solve the multi-user problem. [PDF]

Behav Res Methods
Niehorster DC, Gullberg M, Nyström M.
europepmc   +1 more source

Virtual Twin Approach Using Physiologically Based Pharmacokinetic Modeling to Support Precision Dosing of Valproic Acid in Geriatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang, Dong‐Gyu Heo, Eunjin Hong   +2 more
wiley   +1 more source

Privacy protection of communication networks using fully homomorphic encryption based on network slicing and attributes. [PDF]

Sci Rep
Wang W, Liu R, Cheng S.
europepmc   +1 more source

LLM-Conductor: A Closed-Loop Resource-Adaptive Architecture for Secure LLM Deployment in Industrial Sensor Networks and IIoT Systems. [PDF]

Sensors (Basel)
Xu K, Zhang D, Wang X.
europepmc   +1 more source

Demystifying the virtualization process: A call for standard reporting of virtual modifications to evidence-based psychotherapies, using the FRAME model. [PDF]

Transl Behav Med
Boykin DM, Smith TL, Rakel B, Rodrigues M, Embree J, Woods K, Chaison AD, Dindo L.   +7 more
europepmc   +1 more source

Slice-aware 5G network orchestration framework based on dual-slice isolation and management strategy (D-SIMS). [PDF]

Sci Rep
Venkatapathy S, Srinivasan T, Lee OS, Jayaraman R, Jo HG, Ra IH.   +5 more
europepmc   +1 more source