Results 41 to 50 of about 303,154 (254)

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Meno: Virtue as οὐσία and εἶδος

open access: yesProblemos, 2022
The article is an interpretation of the first part of the Meno (70a-79e), in which Plato deals with the problem of knowledge of virtue. Parmenides’ being, constituted by Justice, becomes a reference point for reflecting on the ontological and cognitive ...
Skirmantas Jankauskas
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

Ethical Foreground and Background in Adult Educator Work

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

Reply to Watson on the social virtue of questioning

open access: yes, 2022
I reply to Lani Watson's recent article on the social virtue of ...
Carter, J. Adam, Lani Watson
core   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon   +9 more
wiley   +1 more source

Does virtue ethics allow us to make better judgments of the actions of others? [PDF]

open access: yes, 2019
Virtue ethics encourages us to judge the actions of others, not merely as right or wrong, but as virtuous (kind, courageous, just, compassionate, etc.) or vicious (cruel, cowardly, unjust, selfish, etc.).
van Zyl, Liezl, Liezl van Zyl
core   +1 more source

Hypocricy of the Rich vs Honesty of the Poor in the English Society of the 18$^\text{th}$ Century

open access: yesArmenian Folia Anglistika, 2020
During the 18th century, life was unpleasant and disturbing due to the Horrible Plague and the Great Fire that attacked England and turned the English society upside down. There was a big gap between the rich and the poor.
Vicky Tchaparian
doaj   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali   +4 more
wiley   +1 more source

John Milton: De l’engagement comme contrainte à l’engagement comme vertu

open access: yesEtudes Epistémè, 2016
In many respects, Milton is the epitome of the committed writer for whom the pen is the weapon he wields in his fight for Truth. Such an obvious statement is nonetheless paradoxical on at least two accounts.
Gilles Sambras
doaj   +1 more source

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