Results 131 to 140 of about 359,484 (337)

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Applying Aristotelian and Confucian Virtue Ethics to Humane Work in the Business Context. [PDF]

Humanist Manag J, 2022
Koehn D.
europepmc   +1 more source

Eliminating Prudential Reasons [PDF]

, 2018
I argue, contrary to the consensus of most contemporary work in ethics, that there are no (fundamentally, distinctively) prudential reasons for action. That is to say: there is no class of reasons for action that is distinctively and fundamentally about ...
Worsnip, Alex
core  

Universal Solvent Escape Strategies for Efficient Curing of Hydrogen‐Bond‐Rich 3D Printing Inks

Advanced Science, EarlyView.
This study developed a new 3D printing method for hydrogen‐bonded polymers by combining solvent replacement, nanoparticles, and optimized printing paths. This allows fast, precise scaffold fabrication. The scaffolds can be easily customized and release therapeutic agents slowly through protonation, enabling personalized bone, blood vessel, and nerve ...
Jie Chen, Qing Zhao, Wentao Fu, Weixian Chen, Xiaoqian Zhang, Gaiying Ye, Qinglei Meng, Liyuan Shao, Qian Ma, Lin Zhao, Ying Zhao, Weihua Guo   +11 more
wiley   +1 more source

Do Virtue Ethicists Parent Poorly?

Feminist Philosophy Quarterly
In this paper, I argue that virtue ethics is unfortunately committed to a developmentally detrimental form of moral evaluation in its traditional iterations.
J. B. Delston
doaj  

Virtue Ethics in a Value-driven World: Seeking the Story. [PDF]

Clin Orthop Relat Res, 2022
Humbyrd CJ.
europepmc   +1 more source

Murdoch’s Platonistic virtue ethics [PDF]

, 2014
In this paper I develop a thesis about normative ethics that we might call Platonistic virtue ethics (PVE): Good agency in the truest and fullest sense presupposes the contemplation of the Form of the Good.
Chappell, Timothy
core   +1 more source

Can hotel employees arise internal whistleblowing intentions? Leader ethics, workplace virtues and moral courage [PDF]

, 2022
Ibrahim M. Mkheimer, Kareem M. Selem, Ali Elsayed Shehata, Kashif Hussain, Marta Pérez-Pérez   +4 more
openalex   +1 more source

EIF5A Couples Translational Control With Transcriptional Reprogramming Through Chromocenter Reorganization During Spermiogenesis

Advanced Science, EarlyView.
The translation factor Eukaryotic translation initiation factor 5A (eIF5A) is essential for male fertility in mice. It supports the translation of proteins crucial for heterochromatin organization and acrosome formation. eIF5A deficiency disrupts chromocenter integrity, increases chromatin accessibility, and causes transcriptional dysregulation ...
Yuling Cai, Tongtong Li, Qian Fang, Ziyou Bao, Feng Kong, Huitao Qi, Hanzhen Li, Mingyu Zhang, Wei Wang, Yongxia Guan, Wenbo Liu, Xiangfeng Chen, Zi‐Jiang Chen, Xiaohua Jiang, Xin Wang, Hongbin Liu   +15 more
wiley   +1 more source

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

Advanced Science, EarlyView.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang, Jun Zhang, Yan Wang, Guoping Chen, Kehui Yuan, Yuan He, Chenchen Li, Sumaira Hanif, Yang Yang, Yanli Wang, Pir Muhammad   +10 more
wiley   +1 more source