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Bacterial fitness shapes the population dynamics of antibiotic-resistant and -susceptible bacteria in a model of combined antibiotic and anti-virulence treatment [PDF]
arXiv, 2014 Bacterial resistance to antibiotic treatment is a huge concern: introduction of any new antibiotic is shortly followed by the emergence of resistant bacterial isolates in the clinic. This issue is compounded by a severe lack of new antibiotics reaching the market.
Dyson, Rosemary J. +3 more
arxiv +5 more sources
Scientific Reports, 2021 Antimicrobial resistance (AMR) is a significant public health threat. With the rise of affordable whole genome sequencing, in silico approaches to assessing AMR gene content can be used to detect known resistance mechanisms and potentially identify novel
M. Feldgarden +11 more
semanticscholar +1 more source
Spread of the blaOXA-48/IncL Plasmid within and between Dogs in City Parks, France
Microbiology Spectrum, 2022 The blaOXA-48/IncL plasmid is increasingly reported in dogs, even in the absence of carbapenem use in animals. In this study, we witnessed the spread of this plasmid within and between dogs sharing the same relaxing area.
Marisa Haenni +4 more
doaj +1 more source
Signal Transduction and Targeted Therapy, 2022 Pseudomonas aeruginosa ( P. aeruginosa ) is a Gram-negative opportunistic pathogen that infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive pulmonary disorder (COPD), cancer, and severe infection requiring ...
Shugang Qin +8 more
semanticscholar +1 more source
Alternatives to Fight Vancomycin-Resistant Staphylococci and Enterococci
Antibiotics, 2021 Gram positive pathogens are a significant cause of healthcare-associated infections, with Staphylococci and Enterococci being the most prevalent ones. Vancomycin, a last resort glycopeptide, is used to fight these bacteria but the emergence of resistance
Benjamin Baëtz +3 more
doaj +1 more source
Pathogenicity and virulence of Staphylococcus aureus
Virulence, 2021 Staphylococcus aureus is one of the most frequent worldwide causes of morbidity and mortality due to an infectious agent. This pathogen can cause a wide variety of diseases, ranging from moderately severe skin infections to fatal pneumonia and sepsis ...
Gordon Y. C. Cheung +2 more
semanticscholar +1 more source
Does virulence assessment of Vibrio anguillarum using sea bass (Dicentrarchus labrax) larvae correspond with genotypic and phenotypic characterization? [PDF]
, 2013 Background: Vibriosis is one of the most ubiquitous fish diseases caused by bacteria belonging to the genus Vibrio such as Vibrio (Listonella) anguillarum. Despite a lot of research efforts, the virulence factors and mechanism of V. anguillarum are still
Bossier, Peter +10 more
core +13 more sources
Pathogenicity and virulence of influenza
Virulence, 2023 Influenza viruses, including four major types (A, B, C, and D), can cause mild-to-severe and lethal diseases in humans and animals. Influenza viruses evolve rapidly through antigenic drift (mutation) and shift (reassortment of the segmented viral genome).
Yuying Liang
semanticscholar +1 more source
Antibiotics, 2023 Despite the fact that the selective pressure of antibiotics on wild birds is supposed to be very weak, they are considered potential vectors of antimicrobial resistance (AMR).
Marisa Haenni +7 more
doaj +1 more source
VFDB 2022: a general classification scheme for bacterial virulence factors
Nucleic Acids Res., 2021 The virulence factor database (VFDB, http://www.mgc.ac.cn/VFs/) is dedicated to presenting a comprehensive knowledge base and a versatile analysis platform for bacterial virulence factors (VFs).
Bo Liu +4 more
semanticscholar +1 more source