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Virulence Factors of Clostridium perfringens
Clinical Infectious Diseases, 1979Clostridium perfringens produces a variety of virulence factors. The mechanism of action of these factors usually falls into one of three groups. Some of these virulence factors, such as the alpha toxin, which is phospholipase C, and the kappa toxin, which is a collagenase, are enzymes that hydrolyze substances essential to the integrity of membranes ...
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Virulence factors of Candida albicans
Trends in Microbiology, 2001Candidiasis is a common infection of the skin, oral cavity and esophagus, gastrointestinal tract, vagina and vascular system of humans. Although most infections occur in patients who are immunocompromised or debilitated in some other way, the organism most often responsible for disease, Candida albicans, expresses several virulence factors that ...
R A, Calderone, W A, Fonzi
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Virulence factors of Entamoeba histolytica
Current Opinion in Microbiology, 1999Recent studies have increased our knowledge of Entamoeba histolytica cell biology and gene regulation. In the ameba, dominant-negative mutations in the Gal/GalNAc lectin affect adhesion and cytolysis, whereas mutations in meromyosin affect cytoskeletal function. Studying these mutant proteins has improved our understanding of the role of these proteins
C A, Gilchrist, W A, Petri
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2017
What is a pathogen? What is a virulence factor? At one time, these were relatively straightforward questions to address. During the late nineteenth century, when Pasteur and Koch were developing the germ theory of disease, a pathogen was simply defined as a microorganism that was capable of causing disease in a host (only human hosts will be considered
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What is a pathogen? What is a virulence factor? At one time, these were relatively straightforward questions to address. During the late nineteenth century, when Pasteur and Koch were developing the germ theory of disease, a pathogen was simply defined as a microorganism that was capable of causing disease in a host (only human hosts will be considered
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2012
Pathogens, such as bacteria, viruses, protozoa and fungi, generate molecules that provide them with a selective advantage, often at the expense of the host. These molecules, or virulence factors, enable pathogens to colonize the host through several mechanisms.
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Pathogens, such as bacteria, viruses, protozoa and fungi, generate molecules that provide them with a selective advantage, often at the expense of the host. These molecules, or virulence factors, enable pathogens to colonize the host through several mechanisms.
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Virulence factors in anaerobic bacteri
European Journal of Clinical Microbiology & Infectious Diseases, 1992Various surface structures can be expressed in Bacteroides fragilis, but little is known about capsular structures in other non-spore-forming anaerobes. Fimbriae have been isolated from Bacteroides fragilis and Porphyromonas gingivalis. The importance of iron-repressible outer membrane proteins as virulence factors in Bacteroides fragilis is under ...
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Campylobacter virulence and survival factors
Food Microbiology, 2015Despite over 30 years of research, campylobacteriosis is the most prevalent foodborne bacterial infection in many countries including in the European Union and the United States of America. However, relatively little is known about the virulence factors in Campylobacter or how an apparently fragile organism can survive in the food chain, often with ...
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Virulence factors of Cryptococcus neoformans
Trends in Microbiology, 1995Cryptococcosis is a serious fungal disease in patients with AIDS or other defects in T-cell-mediated host defenses. Cryptococcus neoformans produces several virulence factors, most notably the polysaccharide capsule and phenol oxidase. Molecular studies of cryptococcal virulence factors have contributed to our understanding of the pathobiology of this ...
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Virulence factors of Bordetella pertussis
Antonie van Leeuwenhoek, 1988Clearly, B. pertussis has evolved very elaborate mechanisms to maintain itself in the human host. Three different proteins (FHA, pertussis toxin and fimbriae) have been implicated in adherence. Furthermore, a number of toxins are produced (pertussis toxin, adenylate cyclase, dermonecrotic toxin, and tracheal cytotoxin) which destroy the clearance ...
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