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Virulence Factors in Anaerobes
Clinical Infectious Diseases, 1994Among the broad spectrum of species of anaerobic bacteria in the normal flora of humans, a few exhibit marked pathogenic potential and are responsible for the majority of infections. The factors that determine the virulence of particular species are varied and probably interrelated.
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Virulence factors of Toxoplasma gondii
Microbes and Infection, 2012Toxoplasma gondii virulence is dependent on factors involved in either parasite-host cell interaction, or in host immune response. It is essentially defined in the mouse and little is known concerning human infection. The genetic dependence of virulence is a growing field, benefiting from the recent development of research of the population structure ...
Jean François, Dubremetz +1 more
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2015
The prevalence of invasive fungal infections has risen significantly worldwide, and although over 600 fungal species are reported as human pathogens, Candida species are arguably the most frequently isolated and the most important cause of morbidity and mortality in humans.
Lindsay E. O’Donnell +2 more
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The prevalence of invasive fungal infections has risen significantly worldwide, and although over 600 fungal species are reported as human pathogens, Candida species are arguably the most frequently isolated and the most important cause of morbidity and mortality in humans.
Lindsay E. O’Donnell +2 more
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Virulence Factors of Clostridium difficile
Clinical Infectious Diseases, 1990In addition to the two major toxins of Clostridium difficile--toxins A and B, which represent the major virulence factors--a number of other putative virulence factors have been described. These factors include fimbriae and the ability to associate with gut cells/mucus, the production of a capsule, the secretion of a range of hydrolytic enzymes, the ...
S P, Borriello +4 more
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Virulence factors of urinary pathogens
Clinical Science, 1986Despite the widespread use of antibiotics urinary tract infections (UTI) remain among the most common bacterial infections in the human population. About 5% of adult females are likely to have a UTI at any moment in time, while more than 50% of all women will experience a UTI at some stage in their lives [l].
M J, Harber, N, Topley, A W, Asscher
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Natural products that target virulence factors in antibiotic resistant Staphylococcus aureus.
Journal of Agricultural and Food Chemistry, 2019The increase in the incidence of antibiotic-resistant Staphylococcus aureus (S. aureus)-associated infections necessitates the urgent development of novel therapeutic strategies and antibacterial drugs. Anti-virulence strategy is an especially compelling
Shuai-Cheng Wu +3 more
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Staphylococcal Virulence Factors
2012The adherence of staphylococci to the unmodified or host factor-coated surface of a medical device is the first critical event in the establishment of a device-associated infection with these serious pathogens. Staphylococcus aureus in particular harbors a variety of proteinaceous and non-proteinaceous adhesins that mediate attachment to a multitude of
Christine Heilmann, Friedrich Götz
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Virulence factors of Mycobacterium bovis
Tuberculosis, 2001Virulence factors of Mycobacterium bovis are the special properties that enable it to infect, survive, multiply and cause disease in an animal host. An understanding of these factors will lead to new strategies including an effective vaccine to control bovine tuberculosis.
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Virulence Factors of Clostridium perfringens
Clinical Infectious Diseases, 1979Clostridium perfringens produces a variety of virulence factors. The mechanism of action of these factors usually falls into one of three groups. Some of these virulence factors, such as the alpha toxin, which is phospholipase C, and the kappa toxin, which is a collagenase, are enzymes that hydrolyze substances essential to the integrity of membranes ...
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Virulence factors of Candida albicans
Trends in Microbiology, 2001Candidiasis is a common infection of the skin, oral cavity and esophagus, gastrointestinal tract, vagina and vascular system of humans. Although most infections occur in patients who are immunocompromised or debilitated in some other way, the organism most often responsible for disease, Candida albicans, expresses several virulence factors that ...
R A, Calderone, W A, Fonzi
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