Comparative genomics and transcriptomics of Escherichia coli isolates carrying virulence factors of both enteropathogenic and enterotoxigenic E. coli [PDF]
, 2017 Escherichia coli that are capable of causing human disease are often classified into pathogenic variants (pathovars) based on their virulence gene content. However, disease-associated hybrid E.
Daugherty, Sean C +6 more
core +2 more sources
Long-chain fatty acids alter transcription of Helicobacter pylori virulence and regulatory genes [PDF]
PeerJ, 2021 Infection with Helicobacter pylori is one of the most important risk factors for developing gastric cancer (GC). The type IV secretion system (T4SS) encoded in the cag pathogenicity island is the main virulence factor of H.
Hilda A. Valdez-Salazar +6 more
doaj +2 more sources
Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence [PDF]
, 2017 Efflux pumps of the resistance-nodulation-cell-division (RND) family increase antibiotic resistance in many bacterial pathogens, representing candidate targets for the development of antibiotic adjuvants.
Baldelli, Valerio +8 more
core +2 more sources
Plants send small RNAs in extracellular vesicles to fungal pathogen to silence virulence genes
Science, 2018 Defense cargo shuttles in vesicles Plants can use small RNAs (sRNAs) to interfere with virulence factor gene expression in pathogens. Cai et al. show that the small mustard plant Arabidopsis shuttles defensive sRNAs into the necrotrophic fungus Botrytis ...
Qiang Cai +7 more
semanticscholar +1 more source
Characterisation of the effects of salicylidene acylhydrazide compounds on type three secretion in Escherichia coli O157:H7 [PDF]
, 2009 Recent work has highlighted a number of compounds that target bacterial virulence by affecting gene regulation. In this work, we show that small-molecule inhibitors affect the expression of the type III secretion system (T3SS) of <i>Escherichia ...
Elofsson, M. +9 more
core +3 more sources
Epigenetic memory at malaria virulence genes [PDF]
Proceedings of the National Academy of Sciences, 2007 During its red blood cell stage, the malaria parasite Plasmodium falciparum can switch its variant surface proteins ( P. falciparum erythrocyte membrane protein 1) to evade the host immune response. The var gene family encodes P.
Thanat, Chookajorn +6 more
openaire +2 more sources
Pseudomonas virulence factor controls expression of virulence genes in Pseudomonas entomophila
PLOS ONE, 2023 Quorum sensing is a communication strategy that bacteria use to collectively alter gene expression in response to cell density. Pathogens use quorum sensing systems to control activities vital to infection, such as the production of virulence factors and biofilm formation.
Katie A. Acken, Bo Li
openaire +3 more sources
The distribution of plasmids that carry virulence and resistance genes in Staphylococcus aureus is lineage associated. [PDF]
, 2012 BACKGROUND: Staphylococcus aureus is major human and animal pathogen. Plasmids often carry resistance genes and virulence genes that can disseminate through S. aureus populations by horizontal gene transfer (HGT) mechanisms. Sequences of S.
Lindsay, JA, McCarthy, AJ
core +2 more sources
Development of ListeriaBase and comparative analysis of Listeria monocytogenes [PDF]
, 2015 Background: Listeria consists of both pathogenic and non-pathogenic species. Reports of similarities between the genomic content between some pathogenic and non-pathogenic species necessitates the investigation of these species at the genomic level to ...
Ang, Mia Yang +9 more
core +3 more sources
Identification of the long polar fimbriae gene variants in the locus of enterocyte effacement-negative Shiga toxin-producing Escherichia coli strains isolated from humans and cattle in Argentina [PDF]
, 2010 The long polar fimbriae (Lpf) is one of few adhesive factors of Shiga toxin-producing Escherichia coli (STEC) and it is associated with colonization of the intestine. Studies have demonstrated the presence of lpf genes in several pathogenic E.
Galli, Lucía +2 more
core +2 more sources