Results 231 to 240 of about 5,926,013 (258)

LAPTM5 Downregulation‐Driven VAMP8 Phosphorylation Impairs Autophagosome‐Lysosome Fusion and Aggravates Septic Acute Lung Injury

Advanced Science, EarlyView.
LAPTM5 functions as a critical molecular scaffold bridging PGAM5 and VAMP to facilitate PGAM5‐mediated dephosphorylation of VAMP8. This cascade promotes autophagosome‐lysosome fusion, restores impaired autophagic flux, and clears damaged mitochondria, thereby mitigating cellular oxidative stress and systemic inflammation.
Lang Jiang, Qilan Li, Hao Liu, Xuehui Gao, Hongyu Nie, Lang Chen, Mei He, Xuefeng Li, Xiangming Fang, Jiqian Xu, Hao Zhang, Jiahong Xia, You Shang   +12 more
wiley   +1 more source

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

Advanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li, Jiayi Li, Ang Dong, Xiaoyan Guo, Qiuyue Tu, Zelin Feng, Haojia Lin, Yanru Zhang, Yuxuan Hao, Huiying Gong, Yihan Meng, Yu Wang, Shing‐Tung Yau, Xiaocang Cao, Rongling Wu, Xinjuan Liu   +15 more
wiley   +1 more source

Mutational landscape and in silico structure models of SARS-CoV-2 Spike Receptor Binding Domain reveal key molecular determinants for virus-host interaction

, 2020
Nelson-Sathi S, Umasankar P, Sreekumar E, Radhakrishnan Nair R, Joseph I, Nori SRC, Philip JS, Prasad R, Navyasree K, Ramesh S, Pillai H, Ghosh S, Santosh Kumar T, Radhakrishna Pillai M.   +13 more
europepmc   +1 more source

Blue Light Receptor PHR2‐Mediated Spectrum Antiviral Immunity

Advanced Science, EarlyView.
Blue light suppresses RBSDV through the blue‐light receptor ZmPHR2, which interacts with ZmISP in chloroplasts to trigger ROS burst and antiviral defense. The viral effector P6 enhances ZmPHR2–ZmISP interaction, alters their distribution, and suppresses ROS.
Runyi Chen, Yuxin Tai, Xinyu Wang, Chunhua Mu, Xia Liu, Gongjian Li, Jiayi Liu, Xin Lu, Duo Shi, Zhiqiang Zhou, Jienan Han, Zhuanfang Hao, Mingshun Li, Degui Zhang, Hongjun Yong, Zhennan Xu, Jianfeng Weng, Xinhai Li   +17 more
wiley   +1 more source

Host-virus interactions dominate fitness and conceal additive genetic variation. [PDF]

PLoS Biol
Belyi A, Du Y, Wilson AJ, Longdon B, Jiggins FM.   +4 more
europepmc   +1 more source

Annexin A6 Interacts with Newcastle Disease Virus Matrix Protein and Is Associated with Reduced Viral Replication in DF-1 Cells. [PDF]

Viruses
Xu H, Chen Y, Hu S, Liu X.
europepmc   +1 more source

Dynamism under the hood: Coevolutionary maintenance of variation in hosts and parasites. [PDF]

PLoS Biol
Graham AL, Chang van Oordt DA.
europepmc   +1 more source

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Aptamer–Protein Interactions: From Regulation to Biomolecular Detection

Chemical Reviews, 2023
Jie Tan, Quan Yuan, Tan Weihong
exaly  

Human Papillomaviruses: Diversity, Infection and Host Interactions

Nature Reviews Microbiology, 2022
Alison A. McBride
exaly