Results 101 to 110 of about 5,037,554 (304)

Redefining the immune landscape of hepatitis A virus infection

Experimental and Molecular Medicine
Despite the development of effective vaccines against hepatitis A virus (HAV) infection, outbreaks of acute hepatitis A still occur globally, such that HAV remains a major cause of acute viral hepatitis.
Ombretta Colasanti, Hosun Yu, Volker Lohmann, Eui-Cheol Shin   +3 more
doaj   +1 more source

Establishment of Primary Transgenic Human Airway Epithelial Cell Cultures to Study Respiratory Virus-Host Interactions. [PDF]

, 2019
Primary human airway epithelial cell (hAEC) cultures represent a universal platform to propagate respiratory viruses and characterize their host interactions in authentic target cells.
Hulda R. Jonsdottir, Rodriguez, Regulo, Dijkman, Ronald, Dirk Geerts, Jonsdottir, Hulda R, Regulo Rodriguez, Thiel, Volker, Ronald Dijkman, Sabrina Marti, Marti, Sabrina, Volker Thiel, Jonsdottir, Hulda R., Geerts, Dirk   +12 more
core   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Revealing the molecular signatures of host-pathogen interactions. [PDF]

, 2011
Advances in sequencing technology and genome-wide association studies are now revealing the complex interactions between hosts and pathogen through genomic variation signatures, which arise from evolutionary co ...
Martin L Hibberd, Khor, C.-C., Hibberd, Martin L, Chiea-Chuen Khor, Hibberd, M.L., Khor, Chiea-Chuen   +5 more
core   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

MNF, an ankyrin repeat protein of myxoma virus, is part of a native cellular SCF complex during viral infection [PDF]

, 2010
Myxoma virus (MYXV), a member of the Poxviridae family, is the agent responsible for myxomatosis, a fatal disease in the European rabbit (Oryctolagus cuniculus).
Camus-Bouclainville, Christelle, Camus-Bouclainville Christelle, Jacqueline Gelfi, Sophie Blanié, Bertagnoli Stéphane, Blanié, Sophie, Gelfi, Jacqueline, Blanié Sophie, Christelle Camus-Bouclainville, Stéphane Bertagnoli, Bertagnoli, Stéphane, Gelfi Jacqueline   +11 more
core   +1 more source

The Development of Rheumatoid Arthritis–Specific Ambulatory Care–Sensitive Conditions: Results of a Consensus Process

Arthritis Care &Research, EarlyView.
Objective Ambulatory care–sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin, Candace H. Feldman, Claire E. H. Barber, Gabriel Fabreau, Jake Jennings, Scott Patten, Cheryl Barnabe, Inflammatory Arthritis‐Specific ACSC Consensus Process Working Group   +7 more
wiley   +1 more source

Transcriptional profiling of zebrafish intestines identifies macrophages as host cells for human norovirus infection

Gut Microbes
Human noroviruses (HuNoVs) are a major cause of diarrheal disease, yet critical aspects of their biology, including cellular tropism, remain unclear.
Emma Roux, Reegan J. Willms, Jana Van Dycke, Álvaro Cortes Calabuig, Lore Van Espen, Geert Schoofs, Jelle Matthijnssens, Johan Neyts, Peter de Witte, Edan Foley, Joana Rocha-Pereira   +10 more
doaj   +1 more source

Utilising proteomic approaches to understand oncogenic human herpesviruses [PDF]

, 2014
The γ‑herpesviruses Epstein-Barr virus and Kaposi's sarcoma‑associated herpesvirus are successful pathogens, each infecting a large proportion of the human population.
Owen, Christopher B, Hughes, DJ, Berndt, Anja, Schumann, Sophie, Whitehouse, A, Jackson, BR, Whitehouse, Adrian, Baquero-Perez, Belinda, Jackson, Brian R, Berndt, A, Owen, CB, Hughes, David J, Baquero-Perez, B, Schumann, S   +13 more
core   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source