Results 241 to 250 of about 233,564 (300)

A first-in-human Phase 1/1b randomized trial evaluating the safety and immunogenicity of a respiratory syncytial virus (RSV) virus-like particle subunit vaccine (IVX-121) in healthy young and older adults. [PDF]

Hum Vaccin Immunother
De Coster I, Leroux-Roels I, Withanage K, Suykens L, D'Onofrio V, Leroux-Roels G, van Damme P, Ciarlet M, Adams EM, Rida W, Wen J, MacDonald M, Price J, Kanesa-Thasan N.   +13 more
europepmc   +1 more source

Marburg virus glycoprotein mRNA vaccine is more protective than a virus-like particle-forming mRNA vaccine. [PDF]

J Clin Invest
Subramani C, Meyer M, Hyde MA, Comeaux ME, Hao H, Crowe JE, Popov VL, Thaker H, Himansu S, Carfi A, Bukreyev A.   +10 more
europepmc   +1 more source

Virus-like particle vaccines targeting a key epitope in circumsporozoite protein provide sterilizing immunity against malaria. [PDF]

NPJ Vaccines
Nepal Y, Francian A, Flores-Garcia Y, Roberts BT, David SA, Zavala F, Chackerian B.   +6 more
europepmc   +1 more source

Virus-like particle encapsulation of functional proteins: advances and applications. [PDF]

Theranostics
Sun X, Lian Y, Tian T, Cui Z.
europepmc   +1 more source

Virus-like particle-based vaccines targeting the Anopheles mosquito salivary protein TRIO. [PDF]

mSphere
Francian A, Flores-Garcia Y, Powell JR, Petrovsky N, Zavala F, Chackerian B.   +5 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Virus-like particles as immunogens

Trends in Microbiology, 2003
Subunit vaccines based on recombinant proteins can suffer from poor immunogenicity owing to incorrect folding of the target protein or poor presentation to the immune system. Virus-like particles (VLPs) represent a specific class of subunit vaccine that mimic the structure of authentic virus particles.
Rob, Noad, Polly, Roy
openaire   +2 more sources

Virus-like particles in leukaemia

Experimental pathology, 1984
Hitherto intracytoplasmic virus-like particles have not been observed simultaneously in nucleus and cytoplasm in human lymphoblasts. We analysed 20 cases of lymphoblastic leukaemia in children and found some virus-like particles in cytoplasm (12 cases) and both in nucleus and cytoplasm (4 cases).
T, Slubowski, M, Kujawa
openaire   +2 more sources

Bioengineering virus‐like particles as vaccines

Biotechnology and Bioengineering, 2013
ABSTRACTVirus‐like particle (VLP) technology seeks to harness the optimally tuned immunostimulatory properties of natural viruses while omitting the infectious trait. VLPs that assemble from a single protein have been shown to be safe and highly efficacious in humans, and highly profitable.
Lua, Linda H. L., Connors, Natalie K., Sainsbury, Frank, Chuan, Yap P., Wibowo, Nani, Middelberg, Anton P. J.   +5 more
openaire   +5 more sources

Enzyme Stabilization by Virus-Like Particles

Biochemistry, 2020
The properties of enzymes packaged within the coat protein shell of virus-like particles (VLPs) were studied to provide a comprehensive assessment of such factors. Such entrainment did not seem to perturb enzyme function, but it did significantly enhance enzyme stability against several denaturing stimuli such as heat, organic solvents, and chaotropic ...
Soumen Das, Liangjun Zhao, Kristen Elofson, M.G. Finn   +3 more
openaire   +2 more sources