Results 241 to 250 of about 187,700 (310)

Biases and complementarity in gut viromes obtained from bulk and virus-like particle-enriched metagenomic sequencing. [PDF]

Microbiol Spectr
Li Y, Sun C, Zhu J, Geng M, Li M, Zhao X-M, Chen W-H.   +6 more
europepmc   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

Passive transfer of human sera from chikungunya virus virus-like particle vaccine (Vimkunya) recipients fully protects non-human primates from viremia. [PDF]

NPJ Vaccines
Morello CS, Anantha R, Comer JE, Mendy J, Tindale LC, Richardson JS, Guenther B, Ho N, Cirimotich CM, Childs O'Connor C, Anderson DM, Bedell L, Warfield KL, Vang L.   +13 more
europepmc   +1 more source

Nasal and Ocular Immunization with Bacteriophage Virus-like Particle Vaccines Elicits Distinct Systemic and Mucosal Antibody Profiles. [PDF]

Vaccines (Basel)
Jamus AN, Wilton ZER, Armijo SD, Flanagan J, Romano IG, Core SB, Frietze KM.   +6 more
europepmc   +1 more source

Post-authorisation experience and reported adverse events following use of a virus-like particle chikungunya vaccine, United States and Germany, up to August 2025. [PDF]

Euro Surveill
Simone B, Lienert F.
europepmc   +1 more source

Marburg virus glycoprotein mRNA vaccine is more protective than a virus-like particle-forming mRNA vaccine. [PDF]

J Clin Invest
Subramani C, Meyer M, Hyde MA, Comeaux ME, Hao H, Crowe JE, Popov VL, Thaker H, Himansu S, Carfi A, Bukreyev A.   +10 more
europepmc   +1 more source

Virus-like particle encapsulation of functional proteins: advances and applications. [PDF]

Theranostics
Sun X, Lian Y, Tian T, Cui Z.
europepmc   +1 more source

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Virus-like particles as immunogens

Trends in Microbiology, 2003
Subunit vaccines based on recombinant proteins can suffer from poor immunogenicity owing to incorrect folding of the target protein or poor presentation to the immune system. Virus-like particles (VLPs) represent a specific class of subunit vaccine that mimic the structure of authentic virus particles.
Rob, Noad, Polly, Roy
openaire   +2 more sources

Virus-like particles in leukaemia

Experimental pathology, 1984
Hitherto intracytoplasmic virus-like particles have not been observed simultaneously in nucleus and cytoplasm in human lymphoblasts. We analysed 20 cases of lymphoblastic leukaemia in children and found some virus-like particles in cytoplasm (12 cases) and both in nucleus and cytoplasm (4 cases).
T, Slubowski, M, Kujawa
openaire   +2 more sources