Results 301 to 310 of about 4,892,090 (362)

Silencing Myostatin Using In Vivo Self‐Assembled siRNA Protects Against Cancer‐ and Dexamethasone‐Induced Muscle Atrophy

Advanced Healthcare Materials, EarlyView.
This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin, Azhar Anwar, Jiehao Chen, Qinghao Sun, Likun Zhou, Jie Tang, Jingwei Guo, Linbo Yan, Yongci Chen, Feng Yin, Chen‐Yu Zhang, Zigang Li, Jizheng Ma, Liyuan Sheng, Xi Chen   +14 more
wiley   +1 more source

Effects of binary ethyleneimine and formaldehyde inactivation methods on foot-and-mouth disease virus vaccine immune responses and kinetics. [PDF]

Sci Rep
Habtewold WT, Welde N, Kenubih A, Getahun YA, Abayneh T, Getachew B, Woldemedhin W, Tesfaye Y, Tesfaw L, Getachew Y, Negussie H.   +10 more
europepmc   +1 more source

Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery

Advanced Healthcare Materials, EarlyView.
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo, Daniel Lozano, Antonio J. Salinas, María Vallet‐Regí   +3 more
wiley   +1 more source

A retrospective investigation for the seroprevalence of Chikungunya virus and its co-existence with Dengue virus in Pakistani population, 2014-2015. [PDF]

Sci Rep
Guhar D, Qadir KA, Khan F, Rehmani SF, Nadeem SG.   +4 more
europepmc   +1 more source

Fabrication of Patterned Composite Microneedles via Inkjet Printing for Enhanced Drug Delivery

Advanced Healthcare Materials, EarlyView.
A novel inkjet printing‐based microneedle platform enabling multi‐material fabrication for customizable and scalable transdermal drug delivery. Abstract Microneedle (MN) technology offers a minimally invasive, patient‐friendly alternative to conventional hypodermic injections for dermal drug delivery.
Sanghyeok Jang, Jooyoung Lee, Hyungseok Lee   +2 more
wiley   +1 more source

AntiviralDB: an expert-curated database of antiviral agents against human infectious diseases. [PDF]

mBio
Huang J, Song Q, Zhang P, Deng L, Gao F, Deng Y, Krol E, Růžek D, Khouri R, De Clercq E, Li G.   +10 more
europepmc   +1 more source

Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials

Advanced Healthcare Materials, EarlyView.
The production of recombinant proteins represents a fundamental step in the characterisation of marine invertebrate adhesives and in the development of bio‐inspired glues. The association of these proteins with other components such as ions, proteins, polysaccharides, or polymers enables the fabrication of biomaterials for various healthcare ...
Alessandra Whaite, Emilie Duthoo, Mathilde Lefevre, Elise Hennebert, Patrick Flammang   +4 more
wiley   +1 more source

Changes to Endemic Respiratory Virus Circulation and Testing Before, During, and After the COVID-19 Pandemic. [PDF]

Open Forum Infect Dis
El-Haddad K, Liu W, Burke P, Wang H, Esper FP.   +4 more
europepmc   +1 more source

Guides for Developing Hundreds of Novel Chiral MXenes and MBenes Nanosheets/Quantum Dots for Next‐Generation Chiral Engineered Biomaterials Applications

Advanced Healthcare Materials, EarlyView.
The emerging field of MXene/MBene materials has progressed rapidly, advancing diverse research fields, including biomedical engineering, biomedicine, agriculture, and the environment. This nanobiotechnology can tackle longstanding challenges in these areas.
Alireza Rafieerad, Ahmad Amiri
wiley   +1 more source

Silent mutations in coding regions of Hepatitis C virus affect patterns of HCV RNA structures and attenuate viral replication and pathogenesis. [PDF]

Genome Biol
Dabour R, Bergman S, Zafrir Z, Davidovitch A, Werbner M, Gal-Tanamy M, Tuller T.   +6 more
europepmc   +1 more source