Results 121 to 130 of about 60,902 (333)

Next generation sequencing for studying viruses and RNA silencing-based antiviral defense in crop plants [PDF]

open access: yes, 2014
The main objectives of this work have been to use next generation sequencing (NGS) and develop bioinformatics tools for plant virus diagnostics and genome reconstruction as well as for investigation of RNA silencing-based antiviral defense.
Seguin, Jonathan
core   +1 more source

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

open access: yesAdvanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding   +13 more
wiley   +1 more source

Evidenciação de vírus patogênicos humanos em filés de peixe Detection of pathogenic virus in fish fillets

open access: yesRevista de Saúde Pública, 1977
Foi desenvolvido método para a evidenciação de vírus em filés de peixe. Amostras de 50 gramas foram submetidas à agitação mecânica durante 5 min em 200 ml de água bidestilada esterilizada, em pH 7,3-7,5.
Ary Walter Schmid   +2 more
doaj   +1 more source

Natural Variation of COLD and CATECHINS REGULATOR 1 Coordinately Fine‐Tunes Cold Tolerance and Tea Quality in Tea Plants

open access: yesAdvanced Science, EarlyView.
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang   +10 more
wiley   +1 more source

Transformation of B Lymphocytes by SV40, a small DNA tumor virus

open access: yes, 2012
For decades we have assessed the risk to humans by the monkey virus SV40, through studies in animal models and humans. While there is increase in the accumulation of opinions over its DNA sequence prevalence in certain human cancers, especially non ...
Alaribe, Franca Nneka
core  

Environmental heterogeneity and the evolution of plant-virus interactions: Viruses in wild pepper populations

open access: yes, 2017
9 Pág.Understanding host-pathogen interactions requires analyses to address the multiplicity of scales in heterogeneous landscapes. Anthropogenic influence on plant communities, especially cultivation, is a major cause of environmental heterogeneity.
Fernando García-Arenal   +11 more
core   +1 more source

Perfusion process with tangential flow filtration for oncolytic VSV-GP production

open access: yesFrontiers in Bioengineering and Biotechnology
The oncolytic vesicular stomatitis (VSV)-GP virus is a promising therapeutic against cancer. To ensure clinical efficacy, doses with high titers are required, which poses a challenge for the manufacturing process.
Orsolya Hamusics   +7 more
doaj   +1 more source

TNFα PRODUCTION AND APOPTOSIS REGULATION IN VIRAL HEPATITIS TYPE C

open access: yesМедицинская иммунология, 2014
. Chronical course of infection caused by hepatitis C virus is accompanied by increase Fas-positive lymphocytes of peripheral blood. Cultivation of agglutinin-stimulated mononuclear blood cells of patients with chronic hepatitis C revealed inhibition of ...
V. V. Novitsky   +8 more
doaj   +1 more source

REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma

open access: yesAdvanced Science, EarlyView.
Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu   +20 more
wiley   +1 more source

Cultivation of Louping Ill Virus

open access: yesExperimental Biology and Medicine, 1933
A simple method1, 2 for the cultivation of vaccine virus was described which consisted of minced viable chick embryo tissue suspended either in Tyrode's solution or in a mixture of Tyrode's solution and rabbit serum. Recently it has been shown that the viruses of vesicular stomatitis3 and poliomyelitis4 are capable of multiplication in media similar to
T. M. Rivers, S. M. Ward
openaire   +1 more source

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