Results 121 to 130 of about 60,902 (333)
Next generation sequencing for studying viruses and RNA silencing-based antiviral defense in crop plants [PDF]
The main objectives of this work have been to use next generation sequencing (NGS) and develop bioinformatics tools for plant virus diagnostics and genome reconstruction as well as for investigation of RNA silencing-based antiviral defense.
Seguin, Jonathan
core +1 more source
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding +13 more
wiley +1 more source
Foi desenvolvido método para a evidenciação de vírus em filés de peixe. Amostras de 50 gramas foram submetidas à agitação mecânica durante 5 min em 200 ml de água bidestilada esterilizada, em pH 7,3-7,5.
Ary Walter Schmid +2 more
doaj +1 more source
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang +10 more
wiley +1 more source
Transformation of B Lymphocytes by SV40, a small DNA tumor virus
For decades we have assessed the risk to humans by the monkey virus SV40, through studies in animal models and humans. While there is increase in the accumulation of opinions over its DNA sequence prevalence in certain human cancers, especially non ...
Alaribe, Franca Nneka
core
9 Pág.Understanding host-pathogen interactions requires analyses to address the multiplicity of scales in heterogeneous landscapes. Anthropogenic influence on plant communities, especially cultivation, is a major cause of environmental heterogeneity.
Fernando García-Arenal +11 more
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Perfusion process with tangential flow filtration for oncolytic VSV-GP production
The oncolytic vesicular stomatitis (VSV)-GP virus is a promising therapeutic against cancer. To ensure clinical efficacy, doses with high titers are required, which poses a challenge for the manufacturing process.
Orsolya Hamusics +7 more
doaj +1 more source
TNFα PRODUCTION AND APOPTOSIS REGULATION IN VIRAL HEPATITIS TYPE C
. Chronical course of infection caused by hepatitis C virus is accompanied by increase Fas-positive lymphocytes of peripheral blood. Cultivation of agglutinin-stimulated mononuclear blood cells of patients with chronic hepatitis C revealed inhibition of ...
V. V. Novitsky +8 more
doaj +1 more source
REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma
Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu +20 more
wiley +1 more source
Cultivation of Louping Ill Virus
A simple method1, 2 for the cultivation of vaccine virus was described which consisted of minced viable chick embryo tissue suspended either in Tyrode's solution or in a mixture of Tyrode's solution and rabbit serum. Recently it has been shown that the viruses of vesicular stomatitis3 and poliomyelitis4 are capable of multiplication in media similar to
T. M. Rivers, S. M. Ward
openaire +1 more source

