Results 171 to 180 of about 55,018 (263)

Mesoporous Silica Nanoparticles‐Based Formulations for Enhanced Oral Delivery of Peptide Drugs: A Case Study on Insulin

Small, EarlyView.
This work explores the tailored functionalization of mesoporous silica nanoparticles (MSN) to improve the oral delivery of insulin, as a case study. Insulin confinement within silica mesopores increased drug solubility, and co‐formulation with succinylated β‐lactoglobulin yielded pH‐responsive tablets that limited gastric release and proteolysis, while
Claudia Iriarte‐Mesa, Estelle Juère, Andrea Bileck, Thomas Kremsmayr, Michael L. Goodson, Allison Ehrlich, Adnan Hodžić, Martin Kunert, Christopher Gerner, Hanspeter Kählig, Doris Marko, Markus Muttenthaler, David Berry, Giorgia Del Favero, Freddy Kleitz   +14 more
wiley   +1 more source

Inhibition of PHF1 promotes ferroptosis via IRES‐dependent Snail translation regulation in pancreatic ductal adenocarcinoma

VIEW, EarlyView.
PHF1 is a known epigenetic regulator involved in transcriptional silencing in cancer. In this study, we identified PHF1 as an oncogene that promotes PDAC progression and demonstrated that its inhibition induces ferroptosis. Mechanistically, PHF1 physically interacts with the FBL/NOP56/NOP58 snoRNP complex to enhance the IRES‐dependent translation of ...
Yujiao Xie, Shan Jin, Yao Zhan, Tiantian Du, Yaqi Dong, Peilong Li, Xiaoshi Zhang, Qiuchen Qi, Jie Gao, Chuanxin Wang   +9 more
wiley   +1 more source

Porcine Cytomegalovirus/Porcine Roseolovirus, Previously Transmitted During Xenotransplantation, Does Not Infect Human 293T and Mouse Cells with Impaired Antiviral Defense. [PDF]

Viruses
Jhelum H, Schäfer R, Kaufer BB, Denner J.   +3 more
europepmc   +1 more source

Trematode infection buffers heat stress in blue mussels Mytilus edulis: The role of heat shock proteins

Journal of Animal Ecology, EarlyView.
The study shows that parasite infection changes heat shock protein expression and can increase heat tolerance in blue mussels. By separating parasite and temperature effects, the results suggest that infection may improve survival during heat stress, highlighting important parasite–host interactions for climate change resilience. Abstract The influence
Annika Greve, Jesper G. Sørensen, Mikael K. Sejr, Jakob Thyrring   +3 more
wiley   +1 more source

Genetically modified foods and human health: a comprehensive review and cross-national time-trend analysis. [PDF]

GM Crops Food
Kim AY, Lee B, Choi DI, Lee HY.
europepmc   +1 more source

THE VIRUS OF VACCINIA AND ITS CULTIVATION. [PDF]

The Lancet, 1898
openaire   +1 more source

Simplified Sample Preparation and Lateral Flow Immunoassay for the Detection of Plant Viruses. [PDF]

Biosensors (Basel)
Tannenberg R, Tscheuschner G, Raab C, Flemig S, Döring S, Ponader M, Thurmann M, Paul M, Weller MG.   +8 more
europepmc   +1 more source

Towards an anthropology of acquisition: ‘How did you get that?’ Vers une anthropologie de l'acquisition : « Où as‐tu trouvé ça ? »

Journal of the Royal Anthropological Institute, EarlyView.
The production‐distribution‐consumption triad has structured how anthropologists understand exchange for roughly a century. This article argues for expanding this triad to include an explicit focus on acquisition – the systems, processes, and practices of acquiring.
Hanna Garth
wiley   +1 more source

STREETS AS STAGES: Traffic Enforcement and the Competition for Cultural Growth in China

International Journal of Urban and Regional Research, EarlyView.
ABSTRACT In keeping with China’s desire to build soft power to parallel its economic growth, the policing of city streets has moved to the forefront as a mechanism for moral regulation and improving urban prestige. Under pressure to civilize their citizenry, many Chinese cities have become entrepreneurial cities within a type of cultural growth ...
Gregory Fayard
wiley   +1 more source