Results 61 to 70 of about 55,018 (263)

A STUDY OF THE ULTRASTRUCTURE OF THE SURFACE OF THE TRANSPLANTABLE LINE VERO CELLS INFECTED WITH THE RABIES VIRUS (RABV, LISSAVIRUS, RHABDOVIRIDAE)

open access: yesВопросы вирусологии, 2017
Characteristics of the effect of attenuated rabies virus strain «Moscow 3253» on morphological parameters of transplantable line Vero cells were studied by atomic force microscopy (AFM).
S. V. Generalov   +6 more
doaj   +1 more source

Egg Cultivated Tumor Protects Embryo against Vaccinia Virus

open access: yesExperimental Biology and Medicine, 1953
Summary1. Yolk sac implants of a dba mouse mammary tumor protected the host embryos against vaccinia virus. A dosage of the virus which killed embryos of nontumor-bearing eggs in 3-4 days gave no evidence of toxicity in the embryos bearing the dba tumor 7 days after inoculation.
A, TAYLOR, N, CARMICHAEL
openaire   +2 more sources

A rational strategy to optimize photodrugs by Molecular Dynamics simulations for killing drug‐resistant Gram‐negative bacteria

open access: yesAIChE Journal, EarlyView.
Abstract Antimicrobial resistance has become a major threat to human health, particularly for Gram‐negative bacteria such as Acinetobacter baumannii and Klebsiella pneumoniae. Disruption of membrane integrity is regarded as a promising antimicrobial strategy that does not induce distinct drug resistance, while increasing the internalization of drug ...
Lei Hao   +10 more
wiley   +1 more source

Hidden diversity of soil giant viruses

open access: yesNature Communications, 2018
Current knowledge of giant virus diversity is largely based on samples from aquatic environments. Here the authors employ cultivation-independent metagenomics and mini-metagenomics on forest soil and identify 16 novel giant virus genomes, some of which ...
Frederik Schulz   +7 more
doaj   +1 more source

Tree shrew model of early diabetic retinopathy reveals microvascular dysfunction and identifies phosphoserine aminotransferase 1 as a novel therapeutic target

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We developed an animal model of early diabetic retinopathy (DR) in the tree shrew by feeding a high‐fat and high‐sugar diet in combination with STZ. Physiological and biochemical index detection, hematoxylin and eosin staining, and transmission electron microscopy were performed to examine DR.
Min Qiu   +10 more
wiley   +1 more source

Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs

open access: yesAdvanced NanoBiomed Research, EarlyView.
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna   +9 more
wiley   +1 more source

Virus-Free Sweet Potato Industry: Development Status and Production Suggestions

open access: yesHorticulturae
Sweet potato (Ipomoea batatas L.) is an important food, feed, and industrial raw material and new energy crop. Its rich nutritional value and health effects are increasingly being recognized by consumers, and the demand is increasing. However, due to the
Ying Xu   +5 more
doaj   +1 more source

Potato Virus Y Detection in Seed Potatoes Using Deep Learning on Hyperspectral Images

open access: yesFrontiers in Plant Science, 2019
Virus diseases are of high concern in the cultivation of seed potatoes. Once found in the field, virus diseased plants lead to declassification or even rejection of the seed lots resulting in a financial loss.
Gerrit Polder   +4 more
doaj   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Fast‐Track to Functional Neurons: Accessible and Minimalistic Neurogenin 2 Programming of Human iPSCs

open access: yesAdvanced NanoBiomed Research, EarlyView.
Fast‐track to functional human induced pluripotent stem cell (hiPSC)‐derived neurons: This colony‐initiated differentiation approach induces neurogenin 2 overexpression in dense hiPSC colonies (day 0), resulting in a structural reorganization of the colonies (day 2) before they are replated as single cells.
Jann Harberts   +9 more
wiley   +1 more source

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