Results 81 to 90 of about 58,318 (254)

Establishment and characterization of mouse lymph node fibrosis models

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu, Xu Guan, Jian Ma, Xin Zhang, Yihang Shi, Jinzhu Zhang, Leiqiong Gao, Wei Chen, Xishan Wang   +8 more
wiley   +1 more source

Cultivation of Louping Ill Virus

Experimental Biology and Medicine, 1933
A simple method1, 2 for the cultivation of vaccine virus was described which consisted of minced viable chick embryo tissue suspended either in Tyrode's solution or in a mixture of Tyrode's solution and rabbit serum. Recently it has been shown that the viruses of vesicular stomatitis3 and poliomyelitis4 are capable of multiplication in media similar to
T. M. Rivers, S. M. Ward
openaire   +1 more source

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

Advanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira, Patrick Opdensteinen, Andrea Simms, Seongwon Jung, Giuliana P. Mognol, Hui Chen, Judith A. Varner, Nicole F. Steinmetz   +7 more
wiley   +1 more source

Perfusion process with tangential flow filtration for oncolytic VSV-GP production

Frontiers in Bioengineering and Biotechnology
The oncolytic vesicular stomatitis (VSV)-GP virus is a promising therapeutic against cancer. To ensure clinical efficacy, doses with high titers are required, which poses a challenge for the manufacturing process.
Orsolya Hamusics, Anja Wittmann, Katrin Hasler, Sabrina Müller, Daniel Birk, Ingo H. Gorr, Alexander Brix, Jorge Soza-Ried   +7 more
doaj   +1 more source

Optimization of Specifications for Scaled-Up Fixed Rabies Virus Cultivation (“Moscow 3253” Strain) in Vero Cell Culture

Проблемы особо опасных инфекций, 2014
/cell, using maintenance media 199 with admixture of 0.1 % human serum albumin or 2 % bovine serum. Optimum media volume in the roll-bottle for fixed rabies virus strain, “Moscow 3253”, cultivation is 200-400 ml. It depends upon the proliferating surface
S. V. Generalov, E. G. Abramova, Zh. V. Matveeva, I. M. Zhulidov, L. V. Savitskaya, O. A. Lobovikova   +5 more
doaj   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

STUDIES ON THE CULTIVATION OF POLIOMYELITIS VIRUS

Uirusu, 1958
It was shown that poliovirus type I (Brunhilde strain) and type III (Nakamura strain) can be serially cultivated over many generations in the developing chick embryo and this can be verified by the interference diagnosis test which is specifically prevented by sera of monkeys taken during the convalescent phase of poliomyelitis.
openaire   +3 more sources

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, EarlyView.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

Health Monitoring of Invasive Pink Salmon Oncorhynchus gorbuscha in Norway in 2023

Aquaculture, Fish and Fisheries
Since 2019, the Norwegian Veterinary Institute (NVI) has conducted health monitoring of pink salmon in Norway. The primary purpose of health monitoring has been to examine the presence of selected notifiable infections in pink salmon, but also to gain ...
Åse Helen Garseth, Lisa Furnesvik, Kristoffer Vale Nielsen, Anne Berit Olsen, Julie Christine Svendsen, Torfinn Moldal   +5 more
doaj   +1 more source

Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA‐Reporter Assay

Arthritis &Rheumatology, EarlyView.
Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki, Masaru Takeshita, Yuki Imai, Hiroyuki Fukui, Kazunori Furuhashi, Kotaro Matsumoto, Jun Kikuchi, Keiko Yoshimoto, Yuko Kaneko   +8 more
wiley   +1 more source