Results 61 to 70 of about 58,318 (254)

A STUDY OF THE ULTRASTRUCTURE OF THE SURFACE OF THE TRANSPLANTABLE LINE VERO CELLS INFECTED WITH THE RABIES VIRUS (RABV, LISSAVIRUS, RHABDOVIRIDAE)

Вопросы вирусологии, 2017
Characteristics of the effect of attenuated rabies virus strain «Moscow 3253» on morphological parameters of transplantable line Vero cells were studied by atomic force microscopy (AFM).
S. V. Generalov, P. S. Erokhin, T. Yu. Krasovskaya, N. A. Osina, E. G. Abramova, A. K. Nikiforov, S. A. Shcherbakova   +6 more
doaj   +1 more source

Experiments in the cultivation of typhus virus

Kazan medical journal, 1935
The subject of this communication is 1) the results of observations on further experiments on growing the typhus virus in yeast cultures, 2) data on the study of the action of immune sera obtained during immunization with the culture virus, and 3) experiments on vaccination of guinea pigs and rabbits with the same virus.
R. R. Geltzer, S. F. Nemshilov
openaire   +1 more source

Targeted Degradation of STING by a Neutrophil Membrane‐Coated Nanoplatform Suppresses Microglial Pyroptosis After Subarachnoid Hemorrhage

Advanced Science, EarlyView.
MG1@NM‐Px serves as a microglia‐targeted STING‐degrading nanoplatform for subarachnoid hemorrhage. Following systemic administration, it crosses the blood–brain barrier and accumulates in activated microglia. STP1‐mediated STING ubiquitination and degradation suppress MAPK/inflammasome signaling, GSDME‐mediated pyroptosis, and IL‐1β release, revealing ...
Ruotian Zhang, Kaikun Yuan, Haoyu Zou, Hanfeng Qin, Jiale Liu, Jianda Sun, Feifan Zhang, Yuankui Wang, Tong Wang, Jiaxing Dai, Chunxu Li, Yichi Chen, Yingfeng Tu, Huaizhang Shi   +13 more
wiley   +1 more source

Hidden diversity of soil giant viruses

Nature Communications, 2018
Current knowledge of giant virus diversity is largely based on samples from aquatic environments. Here the authors employ cultivation-independent metagenomics and mini-metagenomics on forest soil and identify 16 novel giant virus genomes, some of which ...
Frederik Schulz, Lauren Alteio, Danielle Goudeau, Elizabeth M. Ryan, Feiqiao B. Yu, Rex R. Malmstrom, Jeffrey Blanchard, Tanja Woyke   +7 more
doaj   +1 more source

Experiments on the cultivation of the typhoid virus

Kazan medical journal, 1934
Starting experiments on cultivation of typhoid virus on nonpathogenic microorganisms, we settled on yeasts of Saccharomyces cerevisiae-race: M and II species (the yeasts used by Zilber, Vostroukhova and Dosser for cultivation of smallpox vaccine and typhoid virus were not yet known to us). H.
R. R. Geltzer, S. F. Nemshilov
openaire   +1 more source

Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies

Advanced Science, EarlyView.
Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi, Mengsi Lu, Yue Zhang, Anuj Shukla, An‐Li Andrea Ko, Henning J. Jessen   +5 more
wiley   +1 more source

Intratumoral Hypoxia Triggers Mitochondrial BHLHE40 ROS Sensing Pathway to Promote Radioresistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Hypoxia triggers a dual mechanism for BHLHE40 upregulation: reactive oxygen species (ROS)‐dependent post‐translational modification and hypoxia‐inducible factor (HIF)‐dependent transcriptional activation. Under hypoxic conditions, mitochondrial BHLHE40 accumulates and senses ROS via cysteine thiol oxidation and disulfide‐linked homodimer formation ...
Jia Liu, Ziliang Nie, Xi Chen, Guangyu Ji, Yajing Zhang, Zhiqun Zhao, Yuhong Zhang, Xinlong Du, Zhenzhen Zhou, Jiayi Li, Yaozong Yang, Fengqi Sun, Zhibo Yan, Haiquan Lu   +13 more
wiley   +1 more source

Virus-Free Sweet Potato Industry: Development Status and Production Suggestions

Horticulturae
Sweet potato (Ipomoea batatas L.) is an important food, feed, and industrial raw material and new energy crop. Its rich nutritional value and health effects are increasingly being recognized by consumers, and the demand is increasing. However, due to the
Ying Xu, Li-Xiang Wang, Chen Chen, Shao-Shan Ma, Rui Zhou, Ai-Sheng Xiong   +5 more
doaj   +1 more source

Cultivation of Vesicular Stomatitis Virus

Experimental Biology and Medicine, 1933
Carrel, Olitsky, and Long1 reported the successful cultivation of the virus of vesicular stomatitis of horses in 1928. In their cultivation experiments, guinea pig tissues were used throughout. The method they employed consisted in placing embryonic tissue or adult bone marrow in contact with the virus which had been suspended in Tyrode's solution for ...
Cox, H. R., Syverton, J. T., Olitsky, P. K.   +2 more
openaire   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

Advanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma, Rui Wan, Yueyuan Zhong, Ziyang Cui, Xuan Zhang, Xiaoqiang He, Rong Wang, Lei Huang, Wan‐Yang Sun, Rong‐Rong He, Yang Zhou, Jianshuang Li, Li Shen, Shao‐Hua Wang, Tongzheng Liu   +14 more
wiley   +1 more source