Results 81 to 90 of about 55,018 (263)

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Perfusion process with tangential flow filtration for oncolytic VSV-GP production

Frontiers in Bioengineering and Biotechnology
The oncolytic vesicular stomatitis (VSV)-GP virus is a promising therapeutic against cancer. To ensure clinical efficacy, doses with high titers are required, which poses a challenge for the manufacturing process.
Orsolya Hamusics, Anja Wittmann, Katrin Hasler, Sabrina Müller, Daniel Birk, Ingo H. Gorr, Alexander Brix, Jorge Soza-Ried   +7 more
doaj   +1 more source

Optimization of Vaccine Virus Accumulation in the Development of Smallpox Drugs Based on Cell Cultures

Проблемы особо опасных инфекций, 2019
Objective. Optimization of vaccine virus cultivation in the suspended cell culture BHK-21 for infectious activity increment of virus-containing suspension as the base material for smallpox vaccine preparations. Materials and methods.
A. V. Ovchinnikov, G. V. Borisevich, A. I. Terent’ev, Yu. I. Pashchenko, V. T. Krotkov, V. N. Marchenko, S. V. Borisevich, S. L. Kuznetsov   +7 more
doaj   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Shaping research in marine functional connectivity for integrated and effective marine science and management

Biological Reviews, EarlyView.
ABSTRACT Effective knowledge of ecological connectivity at sea and at the land–sea interface is key to supporting global policy goals to conserve and restore ocean biodiversity and function. However, a persistent lack of commonality in terminology and understanding around the concept of connectivity in marine ecological studies hampers its integration ...
Audrey M. Darnaude, Susanne E. Tanner, Andreu Blanco, Anna M. Sturrock, Yael Teff Seker, Angel Pérez‐Ruzafa, Jonne Kotta, Tamar Guy‐Haim, Francisco R. Barboza, Manuel Hidalgo, Katell Guizien, Jerneja Penca, Lucía López‐López, Maria Beger, Federica Costantini, Sophie Arnaud‐Haond, Cynthia Riginos, Kris Hostens, Gil Rilov, Stelios Katsanevakis, Ewan Hunter   +20 more
wiley   +1 more source

Experiments in the cultivation of typhus virus

Kazan medical journal, 1935
The subject of this communication is 1) the results of observations on further experiments on growing the typhus virus in yeast cultures, 2) data on the study of the action of immune sera obtained during immunization with the culture virus, and 3) experiments on vaccination of guinea pigs and rabbits with the same virus.
R. R. Geltzer, S. F. Nemshilov
openaire   +1 more source

The spread of non‐native species

Biological Reviews, EarlyView.
ABSTRACT The global redistribution of species through human agency is one of the defining ecological signatures of the Anthropocene, with biological invasions reshaping biodiversity patterns, ecosystem processes and services, and species interactions globally.
Phillip J. Haubrock, Ali Serhan Tarkan, Irene Martín‐Forés, Stelios Katsanevakis, Ronaldo Sousa, Ismael Soto, Andy J. Green, Antonín Kouba, Teun Everts, Victoria Dominguez Almela, Nadège Belouard, Cang Hui, Jamie Bojko, Victor Deklerck, Margaux Boeraeve, Franz Essl, J. Robert Britton   +16 more
wiley   +1 more source

Subterranean environments contribute to three‐quarters of classified ecosystem services

Biological Reviews, EarlyView.
ABSTRACT Beneath the Earth's surface lies a network of interconnected caves, voids, and systems of fissures forming in rocks of sedimentary, igneous, or metamorphic origin. Although largely inaccessible to humans, this hidden realm supports and regulates services critical to ecological health and human well‐being.
Stefano Mammola, David Brankovits, Tiziana Di Lorenzo, Isabel R. Amorim, Raluca Ioana Bancila, Adrià Bellvert, Enrico Bernard, Anna Blomberg, Paulo A.V. Borges, Martina Cappelletti, Rodrigo Lopes Ferreira, Rosalina Gabriel, Diana M. P. Galassi, Laura Garzoli, Vasilis Gerovasileiou, Grant C. Hose, Kathryn L. Korbel, Simone Martino, Ana Z Miller, Nataša Mori, Veronica Nanni, Giuseppe Nicolosi, Mattia Saccò, Troy S. Sakihara, Marconi Souza Silva, Anne E. Tamalavage, Maja Zagmajster, Efraín Chávez, Christian Griebler, Pedro Cardoso, Alejandro Martínez   +30 more
wiley   +1 more source

Health Monitoring of Invasive Pink Salmon Oncorhynchus gorbuscha in Norway in 2023

Aquaculture, Fish and Fisheries
Since 2019, the Norwegian Veterinary Institute (NVI) has conducted health monitoring of pink salmon in Norway. The primary purpose of health monitoring has been to examine the presence of selected notifiable infections in pink salmon, but also to gain ...
Åse Helen Garseth, Lisa Furnesvik, Kristoffer Vale Nielsen, Anne Berit Olsen, Julie Christine Svendsen, Torfinn Moldal   +5 more
doaj   +1 more source

A roadmap to key traits of invasive Drosophilidae

Biological Reviews, EarlyView.
ABSTRACT Biological invasions have intensified in recent decades, mostly driven by international trade and travel, raising significant concerns, particularly regarding insect pests. Once non‐native species establish, they can disrupt natural ecosystem stability, undermine agroecosystem sustainability and cause substantial economic losses.
Gwenaëlle Deconninck, Bréa Raynaud‐Berton, Méghan Boulembert, Olivier Chabrerie, Aude Couty, Franck Dedeine, Patrice Eslin, Vincent Foray, Romain Georges, Patricia Gibert, Laurence Mouton, Sylvain Pincebourde, David Renault, Christelle Suppo, Hervé Colinet   +14 more
wiley   +1 more source