La cirrosis hepática es una de las enfermedades con mayor prevalencia y mortalidad en la población mundial; sus etiologías más importantes son de tipo alcohólica, el virus de la hepatitis B, el virus de la hepatitis C y la esteatosis hepática no ...
Edgardo Jose Escorcia Charri
doaj +1 more source
Genotipos circulantes del virus de la hepatitis C en Colombia
Introducción. La infección crónica por el virus de la hepatitis C es un problema de salud pública y se estima que hay más de 180 millones de personas infectadas en el mundo.
Óscar Santos +5 more
doaj +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Estado actual de la epidemiología, diagnóstico, tratamiento y control de la hepatitis C
La hepatitis C, infección producida por el virus de la hepatitis C (VHC), que se transmite por sangre, es la principal causa de hepatitis crónica, cirrosis y cáncer del hígado a nivel mundial.
Patricia Velez-Moller
doaj +3 more sources
Transplante hepático en pacientes con cirrosis por VHB y VHC
La cirrosis hepática asociada al virus C constituye la principal indicación de trasplante hepático en Europa y EEUU, representando en adultos hasta el 50% de las indicaciones, mientras que la cirrosis asociada al virus B representa alrededor del 10%. Las
J.F. Lucena, J.I. Herrero
doaj
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle +4 more
wiley +1 more source
Infecciones Oportunistas en Personas con el Virus de la Inmunodeficiencia Humana Paraguay 2010-2016
Determinar la seroprevalencia de infecciones oportunistas (Hepatitis A, Hepatitis B, Hepatitis C, Toxoplasmosis y Citomegalovirus) en personas con VIH (Virus de la Inmunodeficiencia Humana) que fueron diagnosticados e institucionalizados en el Programa ...
Anibal Kawabata +4 more
doaj
Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier +3 more
wiley +1 more source

