The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system. [PDF]
, 1992 Following intracerebral inoculation of adult Balb/c Byj mice, the MHV-4 strain of mouse hepatitis virus (MHV) had an LD50 of less than 0.1 PFU, whereas its monoclonal antibody resistant variant V5A13.1 had an LD50 of 10(4.2) PFU.
Bloom, F +3 more
core +1 more source
Infections with cytomegalovirus and other herpesviruses in 121 liver transplant recipients: Transmission by donated organ and the effect of OKT3 antibodies [PDF]
, 1988 One hundred twenty-one adult liver transplant recipients were studied for the incidence, risk factors, and morbidity associated with herpesviruses infections after transplantation. The overall incidence of infection was 59% for cytomegalovirus (CMV), 35%
Armstrong, JA +7 more
core +1 more source
Desirable Characteristics of Hepatitis C Treatment Regimens: A Review of What We Have and What We Need. [PDF]
, 2016 There have been dramatic advancements in the treatment of chronic hepatitis C (HCV) infection. This is largely due to the approval of several direct-acting antiviral agents (DAAs) from a variety of medication classes with novel mechanisms of action ...
Bidell, Monique R +4 more
core +2 more sources
Rapid decrease in titer and breadth of neutralizing anti-HCV antibodies in HIV/HCV-coinfected patients who achieved SVR [PDF]
, 2019 The main targets for neutralizing anti-hepatitis C virus (HCV) antibodies (HCV-nAbs) are the E1 and E2 envelope glycoproteins. We have studied the characteristics of HCV-nAbs through a retrospective study involving 29 HIV/HCV-coinfected patients who ...
Berenguer, Juan +14 more
core +4 more sources
Phylogeography, Risk Factors and Genetic History of Hepatitis C Virus in Gabon, Central Africa [PDF]
, 2012 BACKGROUND: The epidemiological and molecular characteristics of hepatitis C virus (HCV) infection in the general population have been poorly investigated in Africa.
Besson, Guillaume +8 more
core +8 more sources
Dynamic modelling of hepatitis C virus transmission among people who inject drugs: a methodological review [PDF]
, 2014 Equipment sharing among people who inject drugs (PWID) is a key risk factor in infection by hepatitis C virus (HCV). Both the effectiveness and cost-effectiveness of interventions aimed at reducing HCV transmission in this population (such as opioid ...
Cousien, Anthony +5 more
core +5 more sources
Caracterización de pacientes con Hepatitis C en el servicio de hemodiálisis. Cienfuegos 2019
Medisur, 2021 Fundamento: La infección por el virus de la Hepatitis C ha sido reconocida como problema de salud a nivel mundial.Objetivo: Determinar las características de los pacientes con Hepatitis C que reciben tratamiento en el servicio de hemodiálisis del Centro ...
Lizette Rodríguez Fernández +5 more
doaj
Immune response to vaccines in children with celiac disease [PDF]
, 2017 Celiac disease (CD) is an immune-mediated systemic condition evoked by ingestion of gluten and related prolamines in genetically susceptible subjects. The disease is featured by a variable combination of clinical signs, specific antibodies, HLA-DQ2 and ...
ANANIA, Caterina +4 more
core +1 more source
Revista de Gastroenterología de México, 2013 El genotipo 5 del virus de la hepatitis C (VHC) es sumamente raro; además, existe poca literatura respecto a su tratamiento. Presentamos el caso de un paciente con VHC genotipo 5, que presumiblemente adquirió la enfermedad por medio de transfusión ...
M.A. Rubio-Lezama +3 more
doaj +1 more source
Aspectos Epidemiológicos Del Cáncer De Hígado en Costa Rica Años 1990-2014
Ciencia & Salud, 2022 En la actualidad la afectación por cáncer de hígado ha adquirido una mayor relevancia, ya que a nivel mundial y más específicamente en el Continente Americano, se ha notado un incremento en dicha patología, la cual llega a ocupar un lugar no ...
María Fernanda Pérez Chaves +4 more
doaj +2 more sources