Results 191 to 200 of about 31,546 (239)

SARS‐CoV‐2 enhances lysosomal exocytosis and deacidifies lysosomes to facilitate viral release

mLife, EarlyView.
Abstract The mechanism of SARS‐CoV‐2 egress predominantly governs the quantity and quality of progeny viruses, thereby significantly contributing to viral pathogenicity. However, the key factors influencing viral egress remain largely unclear. In this study, using transcription‐ and replication‐competent SARS‐CoV‐2 virus‐like‐particle (SARS‐CoV‐2 trVLP)
Fujun Qin, Chuang Yan, Zizheng Liu, Dianbing Wang, Huimin Zhong, Qiang Ding, Minghai Chen, Xian‐En Zhang   +7 more
wiley   +1 more source

DNA methylation and gene expression signatures for common childhood infections. [PDF]

Clin Epigenetics
Herrera-Luis E, Sisó DP, Vidal M, Margetaki K, Pissanidis AAK, Aguilar R, Vrijheid M, Dobaño C, Kogevinas M, Karachaliou M, Bustamante M.   +10 more
europepmc   +1 more source

Optimal Control Analysis of Vertically Transmitted Infectious Diseases With Saturated Incidence and Nonlinear Treatment

Optimal Control Applications and Methods, EarlyView.
Schematic representation of the proposed disease transmission model incorporating vertical transmission, saturated incidence, and nonlinear treatment. The study combines theoretical analysis, bifurcation and stability investigations, and optimal control techniques to evaluate prevention and treatment interventions.
Oludolapo A. Olanrewaju, Sulaimon F. Abimbade   +1 more
wiley   +1 more source

Kaposi Sarcoma-Associated Herpesvirus Risk and Disease in Kidney Donors and Transplant Recipients With HIV in the United States. [PDF]

Clin Infect Dis
Nambiar PH, Liang T, Labo N, Hand J, Blumberg EA, Rana MM, Florman S, Haydel B, Morris MI, Schaenman J, Rodrigues MMS, Werbel WA, Bowring MG, Friedman-Moraco RJ, Stock P, Stosor V, Mehta S, Gilbert AJ, Elias N, Mehta SA, Small CB, Haidar G, Malinis M, Pereira MR, Aslam S, Wojciechowski D, La Hoz R, Santos CAQ, Apewokin S, Castillo-Lugo JA, Ranganna K, Morsheimer M, Massie A, Segev DL, Miley W, Marshall V, Whitby D, Tobian AAA, Durand CM.   +38 more
europepmc   +1 more source

Endoscopic Treatment for Esophagogastric Variceal Bleeding in Patients With Acute‐on‐Chronic Liver Failure: An Observational Study

Portal Hypertension &Cirrhosis, EarlyView.
In patients with acute‐on‐chronic liver failure (ACLF), esophagogastric variceal bleeding (EGVB) represents a critical complication associated with high short‐term mortality. This study evaluated the efficacy of endoscopic treatment in this specific population and identified prognostic factors associated with 6‐week rebleeding and mortality.
Yanan Sun, Peng Li, Shibin Zhang, Yuening Zhang, Chunlei Fan, Ajuan Zeng, Yanna Liu, Huiguo Ding   +7 more
wiley   +1 more source

The inhibitory receptor NKG2A is expressed on T-cells during BKPyVANephropathy. [PDF]

Front Immunol
Bargiel K, Desterke C, Dekeyser M, Rabant M, Dutour L, Grosjean A, Tenenhaus A, Vernochet A, Herr F, Durrbach A.   +9 more
europepmc   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

C no more: a prospective single-arm study to evaluate the effectiveness of a nurse and peer-led mobile model of hepatitis C testing and treatment at community corrections offices. [PDF]

Health Justice
Griffin S, Papaluca T, Holmes JA, Reid B, Craigie A, Dicka J, Crawford S, Callus A, Belzer M, Spelman T, Hellard M, Walker S, Stoové M, Thompson AJ, Winter RJ.   +14 more
europepmc   +1 more source