Results 201 to 210 of about 31,546 (239)

When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble

Portal Hypertension &Cirrhosis, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen, Li Ding, Shan Zhao, Weihong Wang, Jing Zhong, Qiang Yan   +5 more
wiley   +1 more source

Lost in translation: interferon-stimulated genes targeting flavivirus protein synthesis. [PDF]

J Virol
Cannac M, Zoladek J, Nisole S.
europepmc   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Community-based integrated care for HIV, viral hepatitis and sexually transmitted infections, Thailand. [PDF]

Bull World Health Organ
Wansom T, Thongmee A, Chittmittrapap S, Saraporn T, Chavalertsakul K, Chotirosniramit N, Pattarakijroongrueng S, Palakawong Na Ayuthaya T, Verachai V, Traisirichok P, Intharabut B, Linn N, Teuansiri R, Kulprayong K, Waesateh A, Lawseng S, Chumwangwapee T, Pattarasuteewong S, Pudpong N, Unchit D, Photipap J, Wongsuwon C, Werapattanawong N, Smahoh S, Sae-Chee P, Phueakchai S, Kittikoonprasert P, Bootsan P, Lawpoolsri S, Creac'H P, Mills S, Yoocharoen P, Avihingsanon A, Phanuphak N, Riewpaiboon A, Durier N, C-Free Study Group..   +36 more
europepmc   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Repurposing GeneXpert® for rapid diagnosis of HPV-associated anal cancer: a case report of an unusually large lesion. [PDF]

Infect Dis Poverty
Bresciani L, Concha-Jaimes J, Díaz-Sheen A, Sabina-Vela JM, Sanchez H, Rojas-Blasquez M, Pinto K, Vassalini P, Ramal-Asayag CJ.   +8 more
europepmc   +1 more source

Applications of chitosan derivatives as adjuvants for nanoparticle‐based vaccines: A comprehensive review

Smart Molecules, EarlyView.
This review highlights how chitosan derivatives enhance nanoparticle‐based vaccines through superior stability, mucoadhesion, and immune modulation. By triggering robust mucosal, humoral, and cellular responses, these biocompatible polymers serve as a transformative platform for next‐generation immunotherapeutics and safe and effective vaccine delivery
Sayantani Dasgupta, Susanta Paul, Swarupananda Mukherjee, Nilanjan Sarkar, Arvind Kumar, Amrita Chakraborty, Anannya Bose, Atanu Hazra, Mainak Chakraborty   +8 more
wiley   +1 more source

Primary liver cancer at tertiary healthcare facility in Guinea: a cross-sectional study. [PDF]

BMC Gastroenterol
Diallo D, Diallo K, Diallo MS, Diallo AT, Sow O, Kadio KJO, Barry TM, Sylla IS, Sylla D, Pineau P.   +9 more
europepmc   +1 more source

One Yeast, Sixteen Synthetic Chromosomes, Infinite Possibilities

Yeast, EarlyView.
ABSTRACT The evolution of the yeast, Saccharomyces cerevisiae, from a genetically tractable model organism to a chassis for genome‐scale engineering represents one of the most influential trajectories in eukaryotic biology. The Synthetic Yeast Genome Project (Sc2.0) embodies the current height of this trajectory, having now delivered functional ...
Edward Archer, Roy S. K. Walker, Paige E. Erpf, Ian T. Paulsen, Isak S. Pretorius   +4 more
wiley   +1 more source

Immunological research landscapes and emerging immune mechanisms in HIV/HBV co-infection: a bibliometric analysis (2014-2024). [PDF]

Front Immunol
Peng A, Waleed K, Qiu L, Wang L, Tong X, Tu Z, Li Z, Cui Y, Hu F, Yang S, Lu L, Huang P.   +11 more
europepmc   +1 more source