Results 161 to 170 of about 43,232 (314)

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

Advanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao, Liqun Zhou, Minhua Zhou, Yu Fang, Haiying Mai, Lingbo Cao, Kun Xu, Yuan Sang, Minyi Chen, Jiewei Huang, Peiyi Huang, Zhipeng Yan, Chao Wang, Zhangshuai Dai, Dichun Huang, Ronghan He, Lijuan Pang, Yunmiao Guo, Ting Gang Chew, Junqi Huang   +19 more
wiley   +1 more source

Pancreatitis aguda grave e infección por el virus de la influenza A (H1N1) en un paciente pediátrico: reporte de caso

, 2015
Diego Rodríguez Schulz, Agustina Martínez, María Belén Guzmán, Hugo Robledo, Patricia Capocasa, Luz Martínez, Analía Garnero   +6 more
openalex   +1 more source

Antiviral susceptibility of clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses from humans in the United States, October 2024 to February 2025. [PDF]

Emerg Microbes Infect
Pascua PNQ, Chesnokov AP, Nguyen HT, Champion C, Gao R, De La Cruz JA, Jang Y, Hatta Y, Guo Z, Uyeki TM, Di H, Stevens J, Davis CT, Gubareva LV.   +13 more
europepmc   +1 more source

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

Advanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee, Yejin Jang, Yujin Kim, Yumi Shin, Ji‐Joon Song, Meehyein Kim, Sangyong Jon   +6 more
wiley   +1 more source

The expanding H5N1 avian influenza panzootic causes high mortality of skuas in Antarctica. [PDF]

Sci Rep
Iervolino M, Günther A, Begeman L, Aguado B, Bestebroer TM, Bellido-Martin B, Coerper A, Fornillo MV, Fusaro B, Ibañez AE, Leijten L, Lisovski S, Mañez MB, Reade A, van Run P, Soto F, Wallis B, Dewar M, Alcamí A, Beer M, Vanstreels RET, Kuiken T.   +21 more
europepmc   +1 more source

CRISPR in MOF Formulation with Enhanced Stability, Activity, and Altered PAM Specificity for Broad‐Spectrum Diagnosis of Bacterial Sepsis

Advanced Science, EarlyView.
CRISPR‐FLEXMO (CRISPR with flexible PAM in MOF encapsulation) integrates a PAM‐relaxed Cas12a K607R enzyme with a manganese‐coordinated MOF for broad‐spectrum diagnosis of bacterial sepsis. The MOF enhances activity and preserves functionality under heat, solvent, and chaotropic stress, supporting long‐term room‐temperature storage.
Tathagata Pal, Zilong Liu, Meera G. Nair, Juhong Chen   +3 more
wiley   +1 more source

Émergence de virus influenza aviaires hautement pathogènes : la triade hôte, microbiote et virus

, 2021
Pierre Bessière
openalex   +1 more source

The award of the “Interbrew-Baillet Latour de la Santé — 2002” prize to Robert M. Krug for outstanding contributions to influenza virus research [PDF]

, 2002
Bertha-Cecilia Ramìrez, Michèle Bouloy, Anne‐Lise Haenni   +2 more
openalex   +1 more source

The Unprecedented Influenza Epidemic of 2024/2025: Overshadowing the COVID-19 Winter Wave and Exploring Viral Interference. [PDF]

Immun Inflamm Dis
Davido B.
europepmc   +1 more source

Behavior‐ and Cell Type‐Specific Cortico‐Striatal Decoupling in a Parkinson's Disease‐Like Mouse Model

Advanced Science, EarlyView.
Utilizing dual‐site fiber photometry, this study examines cortico‐striatal coupling with cell type resolution, identifying behavior‐ and cell type‐specific cortico striatal decoupling and its dopamine‐dependent mechanism in a Parkinson's disease mouse model.
Xu‐Ran Yao, Yang Liu, Wei‐Tong Zheng, Mao‐Qing Huang, Kai‐Wen He   +4 more
wiley   +1 more source