Results 1 to 10 of about 1,749,390 (349)

Type 2 diabetes progression in an adult Ugandan population with new-onset diabetes: an observational prospective study

BMC Primary Care, 2023
Background The rate of progression of type 2 diabetes following diagnosis varies across individuals and populations. Studies investigating the progression of type 2 diabetes in adult African populations with newly diagnosed diabetes are limited. We aimed
Davis Kibirige, Isaac Sekitoleko, William Lumu, Moffat J. Nyirenda   +3 more
doaj   +1 more source

Predictors of incident herpes simplex virus type 2 infections in young women at risk for unintended pregnancy in San Francisco. [PDF]

, 2007
BackgroundYoung women receiving family planning services are at risk for both unintended pregnancy and herpes simplex virus type 2 (HSV-2) infection.MethodsWe performed a secondary analysis using data from a previously published randomized controlled ...
Ahrens, Katherine, Harper, Cynthia C, Kao, Susan, Klausner, Jeffrey D, Moss, Nicholas J, Padian, Nancy, Raine, Tina, Scott, Katherine   +7 more
core   +3 more sources

Rose virus and virus-like diseases

California Agriculture, 1977
Like all vegetatively propagated plants, roses are subject to infection by virus and virus-like diseases that spread during propagating operations. Studies by plant pathologists with the California Department of Food and Agriculture have shown a 14 ...
G Secor, M Kong, G Nyland
doaj  

Analysis of host factor networks during hepatitis B virus infection in primary human hepatocytes

Virology Journal
Background Chronic hepatitis B virus (HBV) infection affects around 250 million people worldwide, causing approximately 887,000 deaths annually, primarily owing to cirrhosis and hepatocellular carcinoma (HCC).
Suhyun Hwangbo, Gahee Kim, Yongwook Choi, Yong Kwang Park, Songmee Bae, Jae Yong Ryu, Wonhee Hur   +6 more
doaj   +1 more source

Essential role of TMPRSS2 in SARS-CoV-2 infection in murine airways

Nature Communications, 2022
The SARS-CoV-2 variant of concern Omicron, has been reported to mainly use the endocytosis pathway for viral entry, bypassing the furin/TMPRSS2 pathway utilised by other variants. Here, the authors test a panel of SARS-CoV-2 variants in TMPRSS2 knock out
Naoko Iwata-Yoshikawa, Masatoshi Kakizaki, Nozomi Shiwa-Sudo, Takashi Okura, Maino Tahara, Shuetsu Fukushi, Ken Maeda, Miyuki Kawase, Hideki Asanuma, Yuriko Tomita, Ikuyo Takayama, Shutoku Matsuyama, Kazuya Shirato, Tadaki Suzuki, Noriyo Nagata, Makoto Takeda   +15 more
doaj   +1 more source

Variation in dengue virus plaque reduction neutralization testing: systematic review and pooled analysis. [PDF]

, 2012
BackgroundThe plaque reduction neutralization test (PRNT) remains the gold standard for the detection of serologic immune responses to dengue virus (DENV).
Cummings, Derek AT, Lessler, Justin, Rainwater-Lovett, Kaitlin, Rodriguez-Barraquer, Isabel   +3 more
core   +3 more sources

The practitioners guide for dealing with the novel Influenza A, H1n1 pandemic

South African Family Practice, 2009
Within three months of its discovery, the new Influenza A (H1n1) swineflu strain has spread to such an extent that a pandemic has been declared by the World Health Organization (WHO). Although most cases seem to be mild, cases of severe disease have also
Marietjie Venter, L. Bloomberg
doaj   +1 more source

Reconstitution of interferon regulatory factor 7 expression restores interferon beta induction in Huh7 cells

Journal of Virology
Abundance of essential components of double-stranded RNA (dsRNA) recognition and the subsequent interferon (IFN) response vary widely between primary human hepatocytes (PHHs) and commonly used cell culture models based on derivatives of Huh7 cells ...
Andreas Betz, Hao-En Huang, Zuguang Gu, Ombretta Colasanti, Teng-Feng Li, Jasper Hesebeck-Brinckmann, Nadine Gillich, Gnimah Eva Gnouamozi, Matthias Schlesner, Florian W. R. Vondran, Stephan Urban, Ralf Bartenschlager, Marco Binder, Volker Lohmann   +13 more
doaj   +1 more source

The detection of 3 ambiguous type 2 vaccine-derived polioviruses (VDPV2s) in Uganda

Virology Journal, 2018
Background The Oral Polio Vaccine (OPV or Sabin) is genetically unstable and may mutate to form vaccine-derived polioviruses (VDPVs). Methods In 2014, two VDPVs type 2 were identified during routine surveillance of acute flaccid paralysis (AFP) cases ...
Mary Bridget Nanteza, Barnabas Bakamutumaho, Annet Kisakye, Prossy Namuwulya, Henry Bukenya, Edson Katushabe, Josephine Bwogi, Charles Rutebarika Byabamazima, Raffaella Williams, Nicksy Gumede   +9 more
doaj   +1 more source

In silico screening and experimental validation identify riboflavin as an RNA-targeted antiviral against SARS-CoV-2

Scientific Reports
This study explored drug repurposing strategies against conserved RNA structures in the SARS-CoV-2 genome to address viral mutation challenges. Conserved RNA elements were computationally identified by aligning 283 SARS-CoV-2 genomes from Korean patients.
Chae-Hong Jeong, Yoo Jin Na, Tae Yong Kim, So Young Lee, Jungyeon Kim, Sangmi Ryou   +5 more
doaj   +1 more source