Results 181 to 190 of about 1,501,773 (255)

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source

Pregnancy as an Opportunity for Hepatitis C Virus Elimination and Eradication. [PDF]

Am J Trop Med Hyg
Boudova S, Tholey D, Fenkel JM, Derman R, Boelig RC.   +4 more
europepmc   +1 more source

Health and economic benefits of achieving hepatitis C virus elimination in Pakistan: A modelling study and economic analysis. [PDF]

PLoS Med, 2021
Lim AG, Scott N, Walker JG, Hamid S, Hellard M, Vickerman P.   +5 more
europepmc   +1 more source

Chronic HBV Infection Disrupts CCL5‐Secreting cNK Cells and Attenuates Liver Accumulation and Activation of DCs and HBV‐Specific T Cells

Advanced Science, EarlyView.
ADORA2A activation suppresses NFκB‐dependent CCL5 production in cNK cells during chronic HBV infection, disrupting intrahepatic DC recruitment and HBV‐specific CD8+ T‐cell differentiation and function. Targeting the ADORA2A/NFκB/CCL5 axis restores antiviral immunity and facilitates HBV clearance.
Ailu Yang, Yucan Wang, Yating Yu, Jing Wu, Cuiping Bao, Zixuan Wang, Qiuju Han, Zhigang Tian, Jian Zhang, Huajun Zhao   +9 more
wiley   +1 more source

Differentiated duopoly with 'elimination by aspects' [PDF]

"Elimination by aspects" (EBA) is a discrete model of probabilistic choice worked out by Tversky in 1972 which supposes that decision makers follow a particular heuristic during a process of sequential choice.
Laurent Reynald-Alexandre
core  

Toward hepatitis C virus elimination using artificial intelligence. [PDF]

Clin Mol Hepatol
Hur MH, Lee JH.
europepmc   +1 more source

Collection, genotyping and virus elimination of cassava landraces from Tanzania and documentation of farmer knowledge. [PDF]

PLoS One, 2021
Ferguson ME, Tumwegamire S, Chidzanga C, Shah T, Mtunda K, Kulembeka H, Kimata B, Tollano S, Stephen M, Mpayo E, Mohamedi S, Kasele S, Palangyo E, Armachius J, Hamad Ali A, Sichalwe K, Matondo D, Masisila F, Matumbo Z, Kidunda B, Arati AC, Muiruri R, Munguti F, Abass A, Abberton M, Mkamilo G.   +25 more
europepmc   +1 more source

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source

A novel multisite model to facilitate hepatitis C virus elimination in people experiencing homelessness. [PDF]

JHEP Rep
Mourad A, McGeer R, Gray E, Bibby-Jones AM, Gage H, Salvaggio L, Charles V, Sanderson N, O'Sullivan M, Bird T, Verma S.   +10 more
europepmc   +1 more source

Make it clean, make it safe: A review on virus elimination via adsorption. [PDF]

Chem Eng J, 2021
Sellaoui L, Badawi M, Monari A, Tatarchuk T, Jemli S, Luiz Dotto G, Bonilla-Petriciolet A, Chen Z.   +7 more
europepmc   +1 more source