Results 51 to 60 of about 1,501,773 (255)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Antibodies Are Not Essential for the Resolution of Primary Cytomegalovirus Infection but Limit Dissemination of Recurrent Virus [PDF]

open access: yes, 1994
Virus shedding from the epithelial cells of the serous acini of salivary glands is a major source for the horizontal transmission of cytomegalovirus. These cells are, different to other tissues, exempt from CD8 T lymphocyte control. CD4 T lymphocytes are
Crnkovic, Irena   +5 more
core   +2 more sources

Study on virus-free propagation of in-vitro leaf organ regeneration for grapes of Sweet Scarlet and Shine Muscat

open access: yesGuoshu xuebao
【Objective】Grapes are highly susceptible to various virus infection. Heat treatment combined with apical meristem culture is currently a commonly used method for virus elimination and is effective against most grape viruses, but it is less effective in ...
ZHANG Yujing   +6 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Economic Analysis of PRRS Virus Elimination from a Herd [PDF]

open access: yes, 2012
A net present value (NPV) analysis was performed to evaluate PRRS virus elimination from individual herds. The NPV analysis conducted for this study is the first analysis of which the authors are aware that accounts for the more severe negative ...
Mowrer, Christine   +9 more
core   +1 more source

Optimization of efficient virus-free regeneration system from shoot apical meristem of tea chrysanthemum

open access: yesXibei zhiwu xuebao
[Objective] In order to optimize the efficient virus elimination and regeneration system from shoot apical meristem of tea chrysanthemum, suitable heat treatment duration and detoxification agents, this study aims to improve the problem of low virus ...
SHI Ziyin   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Virus demyelination [PDF]

open access: yes, 2003
A number of viruses can initiate central nervous system (CNS) diseases that include demyelination as a major feature of neuropathology. In humans, the most prominent demyelinating diseases are progressive multifocal leukoencephalopathy, caused by JC ...
Fazakerley, John K, Walker, Robert
core   +1 more source

Grapevine fleck virus (GFkV) elimination in a selected clone of Vitis vinifera L. cv. Manto Negro and its effects on photosynthesis

open access: yesOENO One, 2014
Aims: The use of healthy propagating material is required to control grapevine viruses. The aim of this work was to eliminate Grapevine fleck virus (GFkV) from a Manto Negro clone, a local grapevine variety, in order to include this material in ...
Josefina Bota   +4 more
doaj   +1 more source

IN VITRO ELIMINATION OF DAHLIA MOSAIC VIRUS BY USING MERISTEM CULTURE, ELECTROTHERAPY AND CHEMOTHERAPY

open access: yesThe Iraqi Journal of Agricultural science, 2020
This study was conducted to investigate the effect of different in vitro techniques on elimination of dahlia mosaic virus. Meristems of Dahlia mosaic virus (DMV) infected dahlias, with 0.2-0.3 mm in length, were cultured on Murashige and Skoog (MS ...
Nerway & et al.
doaj   +1 more source

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