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Assessment of the Benefits and Risks for Engineered Virus Resistance
2010Viral diseases of cultivated crops are responsible for the worldwide loss of billions of US dollars in agricultural productivity every year. Historically, this loss has been reduced or minimized principally by the implementation of specific agricultural/phytosanitary measures, and by the introduction of naturally occurring virus-resistance genes into ...
Thompson, Jeremy R, Tepfer, Mark
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Genetic Engineering for Virus Resistance
2003A wide range of RNA viruses, belonging to 19 families, infect legumes. DNA viruses of the families Geminiviridae and Caulimoviridae and a new genus, Nanovirus cause serious diseases in legumes. Since host resistance genes for virus resistance are rare in pulses, genetic engineering with pathogen-derived genes is pursued as a promising approach in many ...
R. Usha, K. Veluthambi
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BIOHAZARD – Engineering the Change Virus
2008Introducing change into organisations and influencing the way people work is a slow and potentially rewarding task. Adapting to changing circumstances is a key aspect to agile methods and helping others develop healthy habits in this area is often difficult to accomplish.
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Virus-Inspired Function in Engineered Protein Cages
Journal of the American Chemical Society, 2019The structural and functional diversity of proteins combined with their genetic programmability has made them indispensable modern materials. Well-defined, hollow protein capsules have proven to be particularly useful due to their ability to compartmentalize macromolecules and chemical processes. To this end, viral capsids are common scaffolds and have
Thomas G. W. Edwardson, Donald Hilvert
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Oncolytic Herpes Simplex Virus Engineering and Preparation
2011Herpes simplex virus-1 (HSV-1) is an enveloped, double-stranded DNA virus that has been used with modification as an oncolytic virus against a number of tumor types. Modifications that make HSV-1 replication--conditional, i.e., selectively divide in replicating cells make it fulfill a prerequisite criteria for oncolytic viruses.
Pankaj K, Agarwalla, Manish K, Aghi
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Engineered virus-like nanoparticle heparin antagonists
2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2013Virus nanoparticles provide a self-assembling, reproducible multivalent platform that can be chemically and genetically manipulated for the presentation of a wide array of epitopes. Presented herein are engineered bacteriophage Qβ nanoparticles that function as potent heparin antagonists.
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Engineering and Bio/Nanotechnological Applications of Virus Particles
Virus particles (VPs) are naturally evolved nanomachines. Their outstanding molecular structures, physical and chemical properties, and biological activities make them potentially useful for many biomedical or technological applications. Natural VPs such as virions or capsids must, however, be modified by genetic and/or chemical engineering in order toMauricio G, Mateu, Alejandro, Valbuena
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Cervical cancer prevention and control in women living with human immunodeficiency virus
Ca-A Cancer Journal for Clinicians, 2021Vikrant V. Sahasrabuddhe +1 more
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A Fc engineering approach to define functional humoral correlates of immunity against Ebola virus
Immunity, 2021Yoshihiro Kawaoka +2 more
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