Results 131 to 140 of about 1,277,693 (295)
An investigation of the epigenetic and transcriptional changes which follow Epstein-Barr virus infection of germinal centre B cells [PDF]
, 2010 Although Epstein–Barr virus (EBV) usually establishes a harmless infection in human memory B cells, it is implicated in the development of germinal centre (GC) B-cell-derived malignancies, including Hodgkin’s lymphoma (HL).
Leonard, Sarah Miriam
core +2 more sources
Asia-Pacific Journal of Clinical Oncology, EarlyView.This meta‐analysis of 18 studies (3962 patients) demonstrates that nimotuzumab combined with chemoradiotherapy significantly improves overall survival and progression‐free survival in locally advanced head and neck squamous cell carcinoma, without increasing severe toxicity.
Chengzheng Bao +6 more
wiley +1 more source
Association of Epstein-Barr virus with Esophageal Squamous Cell Carcinoma
Middle East Journal of Cancer, 2018 Introduction: Esophageal squamous cell carcinoma is among the leading causes of cancer related deaths within gastrointestinal tumors. There is a growing body of evidence that shows an association between Epstein Barr virus infection and the development ...
Ali Moradi +8 more
doaj
Acta Paediatrica, EarlyView.ABSTRACT Aim To describe age‐specific clinical features and identify predictors of length of hospital stay in children and adolescents with primary Epstein–Barr virus (EBV) infectious mononucleosis (IM). Methods This multicentre retrospective cohort study included all children and adolescents aged 0–17 years with a verified primary EBV infection in the
Lasse H. Nyhegn +5 more
wiley +1 more source
Journal of Medical Case ReportsBackground Recent biomedical research has shown the unusual, multisystem effects of coronavirus disease 2019 in humans. One specific sequela of a primary severe acute respiratory syndrome coronavirus 2 infection is the reactivation of latent viruses in ...
Ashten Duncan +3 more
doaj +1 more source
Trained Immunity in Childhood Vaccination
Acta Paediatrica, EarlyView.Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai +2 more
wiley +1 more source
British Journal of Haematology, EarlyView.Summary Peripheral T‐cell lymphoma, not otherwise specified (PTCL‐NOS), is a heterogeneous nodal T‐ and natural killer (NK)‐cell lymphoma with limited prognostic biomarkers. A subset of PTCL‐NOS characterized by Epstein–Barr virus (EBV) involvement in tumour cells has recently been recognized as EBV‐positive nodal T‐ and NK‐cell lymphoma (EBV+ nPTCL ...
Hyunseok Yoon +14 more
wiley +1 more source
British Journal of Haematology, EarlyView.Summary Immune dysfunction is implicated in the aetiology of Hodgkin lymphoma (HL), but the association between inborn errors of immunity (IEI) and HL remains poorly understood. We conducted a retrospective, register‐based case–control study in Sweden over five decades to investigate the relationship between IEI and HL. Individuals diagnosed with HL in
Agnes Winsa +7 more
wiley +1 more source
Immunological Heterogeneity in Gastric Cancer: Context‐Dependent Role of CD8+ T Cells
Cancer Science, EarlyView.CD8+ T cell infiltration in gastric cancer shows subtype‐dependent prognostic and predictive significance across TCGA molecular subtypes. Its clinical value is context‐dependent and requires integrated immune profiling to guide modern chemoimmunotherapy strategies.
Xiaofei Sun +3 more
wiley +1 more source