Das Epstein-Barr-Virus ( = Epstein-Barr virus) [PDF]
Epstein-Barr virus is an ubiquitous humanpathogenic herpesvirus. It has been identified as the etiologic agent of infectious mononucleosis. In addition it is associated with the cancers nasopharyngeal carcinoma and Burkitt's lymphoma. Like other herpesviruses it infects cells in a lytic way or it persists in a latent state.
Niller, H. H., Wolf, Hans J.
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The immunology of Epstein–Barr virus infection [PDF]
Epstein–Barr virus is a classic example of a persistent human virus that has caught the imagination of immunologists, virologists and oncologists because of the juxtaposition of a number of important properties. First, the ability of the virus to immortalize B lymphocytes in vitro has ...
Moss, Denis J. +4 more
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Immunodominance of lytic cycle antigens in Epstein-Barr virus-specific CD4+ T cell preparations for therapy. [PDF]
Epstein-Barr virus (EBV) is associated with a number of human malignancies. EBV-positive post-transplant lymphoproliferative disease in solid organ and hematopoietic stem cell transplant recipients has been successfully treated by the adoptive transfer ...
Burdach, S. +36 more
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Epstein-Barr Virus LF2: an Antagonist to Type 1 Interferon [PDF]
Upon viral infection, the major defense mounted by the host immune system is activation of the interferon (IFN)-mediated antiviral pathway, which is mediated by IFN regulatory factors (IRFs).
Shin, Young Chul +8 more
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Epstein-Barr Virus and the Eye [PDF]
Epstein-Barr Virus (EBV), also known as Human HerpesVirus-4 (HHV-4), is a γ-type herpesvirus with a global infection prevalence of over 95%.1,2 Infection, which occurs nasopharyngeally via either a...
Emmett T, Cunningham, Manfred, Zierhut
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Relationship Between Non-Hodgkin's Lymphoma and Blood Levels of Epstein-Barr Virus in Children in North-Western Tanzania: A Case Control Study. [PDF]
Non-Hodgkin's Lymphomas (NHL) are common in African children, with endemic Burkitt's lymphoma (BL) being the most common subtype. While the role of Epstein-Barr Virus (EBV) in endemic BL is known, no data are available about clinical presentations of NHL
Rambau, Peter +30 more
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Lymphoid hyperplasia and lymphoma in transgenic mice expressing the small non-coding RNA, EBER1 of Epstein-Barr virus [PDF]
Background. Non-coding RNAs have critical functions in diverse biological processes, particularly in gene regulation. Viruses, like their host cells, employ such functional RNAs and the human cancer associated Epstein-Barr virus (EBV) is no exception ...
Tsimbouri Penelope M. +15 more
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Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells. [PDF]
Cellular and viral microRNAs (miRNAs) are involved in many different processes of key importance and more than 10,000 miRNAs have been identified so far.
Seto, Eri +23 more
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Dynamic early biomarkers predict outcomes in pediatric Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. [PDF]
This study elucidates the critical pathogenic mechanisms of pediatric Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis (EBV‐HLH), where EBV infection triggers a cytokine storm leading to immune cell hyperactivation and tissue damage. Dynamic plasma biomarkers (EBV‐DNA, ferritin, and interferon‐γ) effectively predict treatment response ...
Liu F +9 more
europepmc +2 more sources
Epstein-Barr virus but not cytomegalovirus is associated with reduced vaccine antibody responses in Gambian infants. [PDF]
BACKGROUND: Epstein-Barr virus (EBV) and cytomegalovirus (CMV) are persistent herpesviruses that have various immunomodulatory effects on their hosts. Both viruses are usually acquired in infancy in Sub-Saharan Africa, a region where childhood vaccines ...
Ebrima S Touray +84 more
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