Results 11 to 20 of about 138,634 (297)

The immunology of Epstein–Barr virus infection [PDF]

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2001
Epstein–Barr virus is a classic example of a persistent human virus that has caught the imagination of immunologists, virologists and oncologists because of the juxtaposition of a number of important properties. First, the ability of the virus to immortalize B lymphocytesin vitrohas provided an antigen presenting cell in which all the latent antigens ...
Moss, Denis J., Burrows, Scott R., Silins, Sharon L., Misko, Ihor, Khanna, Rajiv   +4 more
openaire   +6 more sources

Co-expression of Epstein–Barr virus–encoded RNA1 and viral latent membrane protein 1 in osteosarcoma: A novel insight of predictive markers

Tumor Biology, 2020
Epstein–Barr virus is an etiologic agent of several malignancies. In this study, we explored the association of Epstein–Barr virus–encoded RNA1 and Epstein–Barr virus latent membrane protein 1 co-expression with osteosarcoma.
Keykhosro Mardanpour, Mahtab Rahbar, Sourena Mardanpour, Sidegheh Khazaei, Mansour Rezaei   +4 more
doaj   +1 more source

Immunodominance of lytic cycle antigens in Epstein-Barr virus-specific CD4+ T cell preparations for therapy. [PDF]

, 2007
Epstein-Barr virus (EBV) is associated with a number of human malignancies. EBV-positive post-transplant lymphoproliferative disease in solid organ and hematopoietic stem cell transplant recipients has been successfully treated by the adoptive transfer ...
Burdach, S., Witter, K., Boerschmann Heike, Boerschmann, H., Mautner, Josef, Georg W Bornkamm, Adhikary, D., Adhikary, Dinesh, Uta Behrends, Burdach Stefan, Bornkamm, G.W., Mautner, J., Georg W, Andrea Pfünder, Moosmann, A., Witter Klaus, Adhikary Dinesh, Pfünder, Andrea, Dinesh Adhikary, Klaus Witter, Pfünder Andrea, Josef Mautner, Behrends Uta, Stefan Burdach, Moosmann Andreas, Andreas Moosmann, Bornkamm Georg W., Behrends, Uta, Boerschmann, Heike, Burdach, Stefan, Bornkamm, Georg W., Pfünder, A., Witter, Klaus, Behrends, U., Mautner Josef, Moosmann, Andreas, Heike Boerschmann   +36 more
core   +1 more source

Epstein-Barr Virus LF2: an Antagonist to Type 1 Interferon [PDF]

, 2009
Upon viral infection, the major defense mounted by the host immune system is activation of the interferon (IFN)-mediated antiviral pathway, which is mediated by IFN regulatory factors (IRFs).
Shin, Young Chul, Johannsen, Eric, Haas, Juergen, Hyun Joo, Chul, Fossum, Even, Hutt-Fletcher, Lindsay M., Wu, L., Inn, Kyung-Soo, Jung, Jae U.   +8 more
core   +1 more source

Lymphoid hyperplasia and lymphoma in transgenic mice expressing the small non-coding RNA, EBER1 of Epstein-Barr virus [PDF]

, 2010
Background. Non-coding RNAs have critical functions in diverse biological processes, particularly in gene regulation. Viruses, like their host cells, employ such functional RNAs and the human cancer associated Epstein-Barr virus (EBV) is no exception ...
Tsimbouri Penelope M., Philbey, A.W., Philbey, Adrian W, Repellin, C.E, Claire E Repellin, Wilson, J.B., Joanna B Wilson, Repellin, Claire E, Tsimbouri, P.M., Wilson Joanna B., Philbey Adrian W., Tsimbouri, Penelope M, Adrian W Philbey, Penelope M Tsimbouri, Wilson, Joanna B, Repellin Claire E.   +15 more
core   +1 more source

Epstein-Barr Virus and Cancer [PDF]

Clinical Cancer Research, 2004
AbstractEBV was the first human virus to be directly implicated in carcinogenesis. It infects >90% of the world’s population. Although most humans coexist with the virus without serious sequelae, a small proportion will develop tumors. Normal host populations can have vastly different susceptibility to EBV-related tumors as demonstrated by ...
Matthew P, Thompson, Razelle, Kurzrock
openaire   +2 more sources

Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells. [PDF]

, 2010
Cellular and viral microRNAs (miRNAs) are involved in many different processes of key importance and more than 10,000 miRNAs have been identified so far.
Seto, Eri, Walz, Nicole, Moosmann Andreas, Hammerschmidt, W., Grömminger, Sebastian, Andreas Moosmann, Wolfgang Hammerschmidt, Adam Grundhoff, Grömminger, S., Hammerschmidt Wolfgang, Grömminger Sebastian, Seto, E., Hammerschmidt, Wolfgang, Grundhoff Adam, Nicole Walz, Walz, N., Grundhoff, A., Moosmann, A., Walz Nicole, Grundhoff, Adam, Sebastian Grömminger, Seto Eri, Moosmann, Andreas, Eri Seto   +23 more
core   +1 more source

Epstein–Barr virus vaccines [PDF]

Clinical & Translational Immunology, 2015
Epstein–Barr virus (EBV) is the primary cause of infectious mononucleosis (IM) and is associated with epithelial cell malignancies such as nasopharyngeal carcinoma and gastric carcinoma, as well as lymphoid malignancies including Hodgkin lymphoma, Burkitt lymphoma, non‐Hodgkin lymphoma and post‐transplant lymphoproliferative disorder.
openaire   +3 more sources

Relationship Between Non-Hodgkin's Lymphoma and Blood Levels of Epstein-Barr Virus in Children in North-Western Tanzania: A Case Control Study. [PDF]

, 2013
Non-Hodgkin's Lymphomas (NHL) are common in African children, with endemic Burkitt's lymphoma (BL) being the most common subtype. While the role of Epstein-Barr Virus (EBV) in endemic BL is known, no data are available about clinical presentations of NHL
Rambau, Peter, Kamugisha, Erasmus, Nestory Masalu, Maria Raffaella Petrara, Peter Rambau, Petrara Maria, Kamugisha Erasmus, De Rossi Anita, Kidenya Benson, De Rossi, Anita, Kabyemera R., Anita De Rossi, Masalu N., Kamugisha E., Kidenya, Benson, Benson Kidenya, Mwizamholya D., Damas Mwizamuholya, Petrara, Maria Raffaella, Rambau Peter, Mwizamuholya, Damas, Erasmus Kamugisha, Rambau P., Masalu Nestory, Rogatus Kabyemera, Masalu, Nestory, Kabyemera Rogatus, Mwizamuholya Damas, Maria Petrara, Kabyemera, Rogatus, Kidenya B.   +30 more
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Upregulation of Id1 by Epstein-Barr Virus-encoded LMP1 confers resistance to TGFβ-mediated growth inhibition [PDF]

, 2010
Background Epstein-Barr virus (EBV)-encoded LMP1 protein is commonly expressed in nasopharyngeal carcinoma (NPC). LMP1 is a prime candidate for driving tumourigenesis given its ability to activate multiple signalling pathways and to alter the expression
Yanxing Yu, Lawrence S Young, Lo, KW, Dawson, Christopher W., Kwok W Lo, Lo, Angela, Angela KF Lo, Lo, Kwok W., Dawson, Christopher, Young, Lawrence, Yu, Yanxing, Lo, Angela K. F., Young, Lawrence S., Yu, Y, Christopher W Dawson   +14 more
core   +1 more source