The Dual Roles of Regulatory B Cells in Infection, Cancer, and Immunity
Regulatory B cells maintain immune homeostasis via suppressive cytokines and surface molecules like PD‐L1. While beneficially suppressing autoimmunity and promoting transplant tolerance, these identical mechanisms detrimentally attenuate antipathogen and antitumor immune responses.
Anni Feng +3 more
wiley +1 more source
Corrigendum to "Ebstein-Bar Virus (EBV)-Positive diffuse large B-cell vitreoretinal lymphoma: Two cases without overt immunocompromise and review of the literature" [Am J Ophthalmol Case Rep 2025; 40: 102453]. [PDF]
Zafar S, August AH, Milman T, Deaner JD.
europepmc +1 more source
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Abstract Introduction In 2025, the Medicines and Healthcare products Regulatory Agency (MHRA) approved the use of teplizumab (a monoclonal anti‐CD3 antibody) to delay progression from Stage 2 to Stage 3 Type 1 diabetes in the UK. Methods To address the need for clear guidance on managing patients eligible for teplizumab therapy, the British Society of ...
Renuka P. Dias +8 more
wiley +1 more source
Beyond the Usual Suspects: Emerging Associations Between Epstein-Barr Virus Infection/Infectious Mononucleosis and Cancers. [PDF]
Muckian MD +4 more
europepmc +1 more source
ABSTRACT Adult hemophagocytic lymphohistiocytosis (HLH) is a rare, life‐threatening syndrome triggered by various conditions. A nationwide study of the incidence and outcomes of HLH in Denmark over 23 years (2000–2023) was performed. Adults (≥ 18 years) with HLH and triggering diseases were identified in the Danish National Patient Registry and/or the ...
Mads Okkels Birk Lorenzen +8 more
wiley +1 more source
No substantial causal effect of genetic liability to viral infections on subacute thyroiditis: A large-scale Mendelian randomization analysis. [PDF]
Zeng S, Cheng W.
europepmc +1 more source
The pathology of epstein‐barr virus lymphoproliferations
Stefan D. Dojcinov, Matthew R. Pugh
openaire +3 more sources
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto +14 more
wiley +1 more source
Epstein-Barr virus encephalitis in an immunocompetent elderly patient: A case report. [PDF]
Cao L, Chen C.
europepmc +1 more source

