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Epstein-Barr Virus and Astrocytoma
Critical Reviews™ in Oncogenesis, 2019Epstein-Barr virus (EBV) is an established pathogen linked to a wide range of lymphoproliferative disorders and solid tumors. Astrocytoma is one of the most frequent brain tumors in children, adolescents, and young adults. Astrocyte proliferation usually occurs after brain tissue aggression, which may be of different types, including viral infection ...
Freixo, Cristiana +2 more
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The Epstein-Barr Virus Proteins
1988Publisher Summary This chapter reviews the molecular biology of Epstein–Barr virus (EBV) proteins. Genes expressed in the virus-transformed B cells are usually referred to as “latent.” The complex expression of the EBV genome in transformed B cells is likely to reflect a functional diversity of the various expressed proteins.
J, Dillner, B, Kallin
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New England Journal of Medicine, 2000
The Epstein–Barr virus (EBV) was discovered 36 years ago by electron microscopy of cells cultured from Burkitt's lymphoma tissue by Epstein, Achong, and Barr.1 Four years later, in 1968, EBV was shown to be the etiologic agent of heterophile-positive infectious mononucleosis.2 EBV DNA was detected in tissues from patients with nasopharyngeal carcinoma ...
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The Epstein–Barr virus (EBV) was discovered 36 years ago by electron microscopy of cells cultured from Burkitt's lymphoma tissue by Epstein, Achong, and Barr.1 Four years later, in 1968, EBV was shown to be the etiologic agent of heterophile-positive infectious mononucleosis.2 EBV DNA was detected in tissues from patients with nasopharyngeal carcinoma ...
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Pediatrics In Review, 1994
Introduction Virtually all humans become infected with Epstein-Barr virus (EBV). The vast majority of these infections are inapparent, occur early in life, and are associated with lifelong latent infection and persistent shedding of virus.
W A, Durbin, J L, Sullivan
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Introduction Virtually all humans become infected with Epstein-Barr virus (EBV). The vast majority of these infections are inapparent, occur early in life, and are associated with lifelong latent infection and persistent shedding of virus.
W A, Durbin, J L, Sullivan
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European Journal of Internal Medicine, 2011
Epstein-Barr Virus (EBV) infection has the potential to establish life-long, benign infections in their hosts. Although biochemical evidence of hepatocellular damage is common, jaundice is uncommon and complete recovery is the rule. The present study describes clinical characteristics and changes of liver function tests during the course of infectious ...
Diamantis P, Kofteridis +6 more
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Epstein-Barr Virus (EBV) infection has the potential to establish life-long, benign infections in their hosts. Although biochemical evidence of hepatocellular damage is common, jaundice is uncommon and complete recovery is the rule. The present study describes clinical characteristics and changes of liver function tests during the course of infectious ...
Diamantis P, Kofteridis +6 more
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The Epstein-Barr virus in autoimmunity
Springer Seminars in Immunopathology, 1995EBV, which is one of the viruses that most of us live with throughout most of our lifetimes, is capable of inducing autoantibodies reactive with a variety of normal tissue proteins. Because of this, the virus remains a constant threat for autoimmunization during our lifetimes, and this threat is in fact realized in several autoimmune diseases.
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Epstein‐Barr virus and gastric carcinoma
Pathology International, 2010Epstein‐Barr virus (EBV) has been accepted as an infective agent causing gastric carcinoma (GC). Epstein‐Barr virus‐associated GC, comprising nearly 10% of all cases of GC, is the monoclonal growth of EBV‐infected epithelial cells, which express several EBV‐latent genes (latency I program).
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Epstein-barr virus in multiple sclerosis
Current Neurology and Neuroscience Reports, 2009Recent seroepidemiologic and pathologic evidence suggests that prior infection with Epstein-Barr virus (EBV) may be necessary for the development of multiple sclerosis (MS). EBV infects more than 90% of all humans, most of whom remain healthy. In contrast, 99% of MS patients have evidence of prior infection with EBV.
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Epstein–Barr virus-associated lymphomas
Expert Review of Anti-infective Therapy, 2006Following Epstein and colleagues' ground-breaking discovery of Epstein-Barr virus by electron microscopy of Burkitt's lymphoma cell lines, there came the observation that Epstein-Barr virus induces immortalization of B cells in vitro. Thus, initial hopes were of a virus confined to equatorial Africa with a causal link to a particular subtype of ...
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