Mutation and Epistasis in Influenza Virus Evolution
Influenza remains a persistent public health challenge, because the rapid evolution of influenza viruses has led to marginal vaccine efficacy, antiviral resistance, and the annual emergence of novel strains.
Daniel M. Lyons, A. Lauring
semanticscholar +1 more source
Mosquitoes Transmit Unique West Nile Virus Populations during Each Feeding Episode
Arthropod-borne viruses (arboviruses), such as Zika virus, chikungunya virus, and West Nile virus (WNV), pose continuous threats to emerge and cause large epidemics.
Nathan D. Grubaugh +9 more
doaj +1 more source
Discovery of Two Novel Negeviruses in a Dungfly Collected from the Arctic
Negeviruses are a proposed group of insect-specific viruses that can be separated into two distinct phylogenetic clades, Nelorpivirus and Sandewavirus.
Gang Lu +11 more
doaj +1 more source
SARS-CoV-2 variants: Impact on biological and clinical outcome
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that was first identified in December 2019, in Wuhan, China was found to be the etiological agent for a novel respiratory infection that led to a Coronavirus Induced Disease named COVID-19.
Shakuntala Mahilkar +13 more
doaj +1 more source
Global patterns of avian influenza A (H7): virus evolution and zoonotic threats
Avian influenza viruses (AIVs) continue to impose a negative impact on animal and human health worldwide. In particular, the emergence of highly pathogenic AIV H5 and, more recently, the emergence of low pathogenic AIV H7N9 have led to enormous ...
M. Naguib +10 more
semanticscholar +1 more source
The Revisited Genome of Bacillus subtilis Bacteriophage SPP1
Bacillus subtilis bacteriophage SPP1 is a lytic siphovirus first described 50 years ago. Its complete DNA sequence was reported in 1997. Here we present an updated annotation of the 44,016 bp SPP1 genome and its correlation to different steps of the ...
Lia M. Godinho +10 more
doaj +1 more source
Clinical-evolutional particularities of the cryoglobulinemic vasculitis in the case of a patient diagnosed with hepatitis C virus in the predialitic phase [PDF]
Hepatitis C virus (HCV) represents a fundamental issue for public health, with long term evolution and the gradual appearance of several complications and associated pathologies.
Boldeanu, Lidia +12 more
core +3 more sources
Linking influenza virus evolution within and between human hosts
Influenza viruses rapidly diversify within individual human infections. Several recent studies have deep-sequenced clinical influenza infections to identify viral variation within hosts, but it remains unclear how within-host mutations fare in the global
Katherine S. Xue, J. Bloom
semanticscholar +1 more source
: Infectious Bursal Disease is a highly contagious disease that affects young chickens and leads to significant economic losses. Its causal agent is a double-stranded RNA virus that, due to its high error rate during the replication process, gives rise ...
Juan Jaton +6 more
doaj +1 more source
Contact transmission of influenza virus between ferrets imposes a looser bottleneck than respiratory droplet transmission allowing propagation of antiviral resistance [PDF]
Influenza viruses cause annual seasonal epidemics and occasional pandemics. It is important to elucidate the stringency of bottlenecks during transmission to shed light on mechanisms that underlie the evolution and propagation of antigenic drift, host ...
Ashcroft, J +12 more
core +1 more source

