Results 81 to 90 of about 3,988,806 (312)

SARS-CoV-2 Variants from Long-Term, Persistently Infected Immunocompromised Patients Have Altered Syncytia Formation, Temperature-Dependent Replication, and Serum Neutralizing Antibody Escape

open access: yesViruses
SARS-CoV-2 infection of immunocompromised individuals often leads to prolonged detection of viral RNA and infectious virus in nasal specimens, presumably due to the lack of induction of an appropriate adaptive immune response.
Camille Wouters   +10 more
doaj   +1 more source

Subterranean Clover Stunt Virus Revisited: Detection of Two Missing Genome Components

open access: yesViruses, 2019
Subterranean clover stunt virus (SCSV) is a type species of the genus Nanovirus in the family Nanoviridae. It was the first single-stranded DNA plant virus with a multipartite genome, of which genomic DNA sequences had been determined.
Dennis Knierim   +9 more
doaj   +1 more source

Virus Evolution and Genetics

open access: yes, 2017
Viruses are very diverse and they infect organisms from all domains of life and across all ecosystems, but related viruses often infect very different types of organisms, pointing to their very ancient origins. Three commonly proposed mechanisms for the origins of viruses are: Viruses descended from primitive precellular life forms; viruses are escaped
openaire   +1 more source

Expanding networks of RNA virus evolution [PDF]

open access: yesBMC Biology, 2012
In a recent BMC Evolutionary Biology article, Huiquan Liu and colleagues report two new genomes of double-stranded RNA (dsRNA) viruses from fungi and use these as a springboard to perform an extensive phylogenomic analysis of dsRNA viruses. The results support the old scenario of polyphyletic origin of dsRNA viruses from different groups of positive ...
Koonin Eugene V, Dolja Valerian V
openaire   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Generation of enhanced gene delivery vectors by directed evolution of adeno-associated virus [PDF]

open access: yes, 2006
Despite promising advance in the development of viral vectors based on AAV for human gene therapy, several major hurdles for a more general use remain.
Endell, Jan
core   +1 more source

Genetic Diversity of Infectious Bronchitis Virus Genotype II in Poland

open access: yesPathogens
The epidemiological situation in Poland for IBV GII (formerly known as D1466) has seemed stable over the years, but an increase in such infections has been recently reported. In this study, genetic characterization of the representatives of this genotype
Anna Pikuła   +3 more
doaj   +1 more source

Emergence and adaptive evolution of Nipah virus [PDF]

open access: yesTransboundary and Emerging Diseases, 2019
Since its first emergence in 1998 in Malaysia, Nipah virus (NiV) has become a great threat to domestic animals and humans. Sporadic outbreaks associated with human-to-human transmission caused hundreds of human fatalities. Here, we collected all available NiV sequences and combined phylogenetics, molecular selection, structural biology and receptor ...
Kemang Li   +11 more
openaire   +2 more sources

Pseudorabies Virus

open access: yes, 2022
Pseudorabies virus (PRV) is an important swine pathogen that impacts swine industry worldwide. PRV belongs to the alphaherpes virus subfamily of the herpesviruses that has been widely used as a model herpes virus.

core   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

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