Results 51 to 60 of about 61,434 (287)

The Internal Organization of the Varicella-Zoster Virus Genome

Journal of General Virology, 1982
DNA was extracted from varicella-zoster (VZ) virions prepared in sucrose gradients. Thirty-eight molecules examined by electron microscopy were found to have a mean length of 46.7 micrometers. Examination of self-annealed VZV DNA molecules revealed that the virus genome was composed of a unique linear large sequence with a mol. wt.
D H, Gilden, Y, Shtram, A, Friedmann, M, Wellish, M, Devlin, N, Fraser, Y, Becker   +6 more
openaire   +2 more sources

A Ca2+-dependent signalling circuit regulates influenza A virus internalization and infection [PDF]

, 2013
Various viruses enter host cells via endocytosis, but the molecular mechanisms underlying the specific internalization pathways remain unclear. Here we show that influenza A viruses (IAVs) enter cells via redundant pathways of clathrin-mediated and ...
Miyazaki, Tadaaki, Hattori, Tomoe, Ohba, Yusuke, Tsuda, Masumi, Fujioka, Yoichiro, Sasaki, Junko, Nanbo, Asuka, Sasaki, Takehiko   +7 more
core   +1 more source

Methods for Studying Endocytotic Pathways of Herpesvirus Encoded G Protein-Coupled Receptors

Molecules, 2020
Endocytosis is a fundamental process involved in trafficking of various extracellular and transmembrane molecules from the cell surface to its interior. This enables cells to communicate and respond to external environments, maintain cellular homeostasis,
Maša Mavri, Katja Spiess, Mette Marie Rosenkilde, Catrin Sian Rutland, Milka Vrecl, Valentina Kubale   +5 more
doaj   +1 more source

Anti-BVDV Activity of Traditional Chinese Medicine Monomers Targeting NS5B (RNA-Dependent RNA Polymerase) In Vitro and In Vivo

Molecules, 2023
Natural products have emerged as “rising stars” for treating viral diseases and useful chemical scaffolds for developing effective therapeutic agents.
Nannan Chen, Dongjun Jiang, Baihui Shao, Tongtong Bai, Jinwei Chen, Yu Liu, Zecai Zhang, Yulong Zhou, Xue Wang, Zhanbo Zhu   +9 more
doaj   +1 more source

8th International Conference on Oncolytic Virus Therapeutics

Human Gene Therapy, 2014
The 8th International Conference on Oncolytic Virus Therapeutics meeting was held from April 10-13, 2014, in Oxford, United Kingdom. It brought together experts in the field of oncolytics from Europe, Asia, Australasia, and the Americas and provided a unique opportunity to hear the latest research findings in oncolytic virotherapy.
Guinn, Barbara-Ann, Braidwood, Lynne, Parker, Alan, Peng, Kah-Whye, Seymour, Leonard   +4 more
openaire   +3 more sources

Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. [PDF]

, 2009
Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI).
Balfe, Peter, Hu, K., Mee, C.J., Mee, Christopher J, Schwarz, A.K., Mee, Christopher, Grove, Joe, Balfe, P., Hu, Ke, Schwarz, Anne K, McKeating, Jane A, McKeating, Jane, Schwarz, AK, Grove, Joseph, Grove, J., McKeating, J.A.   +15 more
core   +1 more source

Resolving the APN controversy in PEDV infection: Comparative kinetic characterization through single-virus tracking.

PLoS Pathogens
Aminopeptidase N (APN) plays multiple roles in various physiological processes, with its function as a viral receptor in several coronaviruses being one of the most prominent.
Da An, Yan Li, Yi Pei, Yong-Hao Ma, Fei Yao, Yongzhi Feng, Yanke Shan, Fei Liu   +7 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The Internal Structure of Influenza Virus

Zeitschrift für Naturforschung B, 1959
Auf Grund von physikalischen, chemischen und serologischen Untersuchungen wird ein Modell der inneren Struktur des Influenza-Virus entwickelt, das in Übereinstimmung mit dem elektronenmikroskopischen Bild ist.
openaire   +2 more sources

A Review on the Novel Corona Virus with International and Indian Perspective

Journal of Drug Delivery and Therapeutics, 2021
On 31 December 2019, pneumonia of unknown cause was detected in Wuhan, China, and was first reported to the WHO Country Office in China. On 30 January 2020, the outbreak was declared a Public Health Emergency of International Concern. 1 It was an outbreak of severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infection that occurred in ...
Gayatri Suresh K P,, Thabit Ahmed, mohamed mohammed saeed, Jereish Varghese Daivamthadathil, Anandu Jayan, Jerin Reji Samuel   +5 more
openaire   +2 more sources