Results 31 to 40 of about 778,919 (247)

Vaccine potential of Nipah virus-like particles. [PDF]

PLoS ONE, 2011
Nipah virus (NiV) was first recognized in 1998 in a zoonotic disease outbreak associated with highly lethal febrile encephalitis in humans and a predominantly respiratory disease in pigs.
Pramila Walpita, Jennifer Barr, Michael Sherman, Christopher F Basler, Linfa Wang   +4 more
doaj   +1 more source

Virus-Like Particles Assembled Using Respiratory Syncytial Virus Matrix Protein Elicit Protective Immunity in Mice

Infection and Drug Resistance, 2023
Su-Hwa Lee,1,* Ki-Back Chu,2,* Min-Ju Kim,3 Fu-Shi Quan1,2 1Department of Medical Zoology, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; 2Medical Research Center for Bioreaction to Reactive Oxygen Species and Biomedical ...
Lee SH, Chu KB, Kim MJ, Quan FS
doaj  

Optimizing the synthesis and purification of MS2 virus like particles

Scientific Reports, 2021
Introducing bacteriophage MS2 virus-like particles (VLPs) as gene and drug delivery tools increases the demand for optimizing their production and purification procedure.
Khadijeh Hashemi, Mohammad Mahdi Ghahramani Seno, Mohammad Reza Ahmadian, Bizhan Malaekeh-Nikouei, Mohammad Reza Bassami, Hesam Dehghani, Amir Afkhami-Goli   +6 more
doaj   +1 more source

Dual-acting stapled peptides target both HIV-1 entry and assembly [PDF]

, 2013
Background: Previously, we reported the conversion of the 12-mer linear and cell-impermeable peptide CAI to a cell-penetrating peptide NYAD-1 by using an i,i + 4 hydrocarbon stapling technique and confirmed its binding to the C-terminal domain (CTD ...
Bhargava, P., Cooper, A., Curreli, F., Debnath, A.K., Freed, E.O., Lee, S., Mehta, M., Mercredi, P.Y., Scacalossi, D., Summers, M.F., Tong, X., Waheed, A.A., Zhang, H.   +12 more
core   +2 more sources

The SARS-CoV-2 envelope and membrane proteins modulate maturation and retention of the spike protein, allowing assembly of virus-like particles

Journal of Biological Chemistry, 2020
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a β-coronavirus, is the causative agent of the COVID-19 pandemic. Like for other coronaviruses, its particles are composed of four structural proteins: spike (S), envelope (E), membrane (M)
B. Boson, V. Legros, Bingjie Zhou, Eglantine Siret, C. Mathieu, F. Cosset, Dimitri Lavillette, S. Denolly   +7 more
semanticscholar   +1 more source

The Antitumor Efficacy of CpG Oligonucleotides is Improved by Encapsulation in Plant Virus‐Like Particles

Advanced Functional Materials, 2020
Oligodeoxynucleotides (ODNs) with CpG motifs have potent immunostimulatory effects on many subsets of immune cells. For example, Class B CpG‐ODNs, such as ODN1826 induce the phagocytic activity of macrophages by activating the Toll‐like receptor 9 ...
Hui Cai, Sourabh Shukla, N. Steinmetz
semanticscholar   +1 more source

Unnatural Amino Acid Incorporation into Virus-Like Particles [PDF]

, 2008
Virus-like particles composed of hepatitis B virus (HBV) or bacteriophage Qβ capsid proteins have been labeled with azide- or alkyne-containing unnatural amino acids by expression in a methionine auxotrophic strain of E. coli.
Brown, Steven, Carragher, Bridget, Finn, M. G., Lander, Gabriel, Link, A. James, Ngo, John T., Potter, Clinton S., Prasuhn, Duane E., Quispe, Joel, Strable, Erica, Tirrell, David A., Udit, Andrew K.   +11 more
core   +2 more sources

Influenza Virus Like Particles (VLPs): Opportunities for H7N9 Vaccine Development

Viruses, 2020
In the midst of the ongoing COVID-19 coronavirus pandemic, influenza virus remains a major threat to public health due to its potential to cause epidemics and pandemics with significant human mortality.
Peter Pushko, Irina Tretyakova
doaj   +1 more source

Population dynamics of an RNA virus and its defective interfering particles in passage cultures [PDF]

, 2010
Background Viruses can fall prey to their defective interfering (DI) particles. When viruses are cultured by serial passage on susceptible host cells, the presence of virus-like DI particles can cause virus populations to rise and fall, reflecting ...
Kristen Thompson, John Yin
core   +2 more sources

Thermal remodelling of Alternanthera mosaic virus virions and virus-like particles into protein spherical particles.

PLoS ONE, 2021
The present work addresses the thermal remodelling of flexible plant viruses with a helical structure and virus-like particles (VLPs). Here, for the first time, the possibility of filamentous Alternanthera mosaic virus (AltMV) virions' thermal transition
Tatiana I Manukhova, Ekaterina A Evtushenko, Alexander L Ksenofontov, Alexander M Arutyunyan, Angelina O Kovalenko, Nikolai A Nikitin, Olga V Karpova   +6 more
doaj   +1 more source